This review of the malignant transformation rate of oral leukoplakia included 24 studies, the majority of which were retrospective. The range of malignant transformation was between 0.13% and 34.0%. The quality of the available data was limited and there is a need for higher quality well-reported studies.
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This review of photodynamic therapy (PDT) for oral premalignant lesions only identified a small number of poor quality studies that provide insufficient evidence for the effectiveness of PDT for the management of oral premalignant lesions.
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The aims of the study were to determine how frequently oral potentially malignant disorders (OPMDs) transform to cancer and to identify clinical and histological factors determining the rates of transformation. The study cohort included 1357 patients with biopsy-confirmed OPMDs seen at Guy’s Hospital between 1990 and 1999 and followed up until 2005. The patients’ details [read the full story…]
