Antipsychotics were discovered as an effective treatment for schizophrenia in the 1950s, but their use was expanded despite lack of supporting evidence, to treat other patient groups. This included treating aggression, agitation and other behavioural and psychological symptoms of dementia (BPSD). There is evidence that these distressing symptoms can often be prevented or managed without [read the full story…]
The cardiovascular safety of dementia medications: a cross national study
Two of the most widely available medicines for dementia in the UK are cholinesterase inhibitors and a N-methyl-D-aspartate (NMDA) receptor antagonists (NHS, 2013). Both drugs are popular because they have been found to lead to improvements in dementia symptoms (Raina 2008). However, some have raised concerns about the safety for patients. These concerns are partly [read the full story…]
Short-term recovery from mild cognitive impairment is possible, but an increased risk of further cognitive decline remains
The symptoms of mild cognitive impairment (MCI) include problems with cognitive functioning such as day-to-day memory. In some individuals it is the first sign of dementia, whereas in others it may be due to resolvable factors such as being the side-effect of medication (Alzheimer’s Society, 2012). At present it is unclear how many people with [read the full story…]
CBT is better than nothing for older adults with depression, but so is any form of active support
Depression is such a widely known issue now that it barely needs introduction. It’s something we Elves have covered with interest, looking at the effectiveness of various treatments, like psychotherapy, medication and exercise. For older adults though, there remains a somewhat hazy picture of what treatments work best. Most of the evidence base for the [read the full story…]
Depression and bipolar disorder linked to an increased risk of developing dementia, says systematic review
Dementia and affective disorders (such as depression and bipolar disorder) are usually considered to be completely unrelated afflictions. Yet a number of recent studies have suggested that the risk of developing dementia in later life may be increased for those who have had an affective disorder. A number of systematic reviews have been undertaken to [read the full story…]
NICE publish dementia commissioning guide: practical advice for commissioners
NICE have published a new guide to help commissioners provide evidence-based care for people with dementia. Providing care for our ageing population seems not to have been out of the news in recent years and rightly so, especially as the headline stories are frequently not positive. A recent Care Quality Commission report found that people [read the full story…]
New RCT says antidepressants should not be used when treating depression in dementia
Dementia is one of the most common and serious disorders in later life. It places a considerable burden on the health care system, individuals and especially unpaid carers. Depression is common among people with dementia and causes additional distress to affected individuals and their social circle. Research into the treatment of depression in dementia is [read the full story…]
A fine VINTAGE? The benefits and consequences of alcohol consumption in older adults
We know a lot about the health consequences of drinking too much alcohol, but most of this research comes from studies of adults in their twenties, thirties and forties. But what about older adults? The European project VINTAGE reviewed and synthesised the available evidence relating to alcohol consumption in older people across many European countries. [read the full story…]
Non-drug treatments delivered by family carers can improve neuropsychiatric symptoms in people with dementia
About three-quarters of people with dementia are affected by neuropsychiatric symptoms (NPS). This is a broad group of symptoms including depression, sleep problems, apathy, psychosis and aggression. Of course, many people with dementia still live at home and are cared for by their spouse or other primary carer. These neuropsychiatric symptoms can have a major impact [read the full story…]
Cerebrolysin is a promising treatment for vascular dementia, but more research is needed, according to new Cochrane review
Vascular dementia is the second most common type of dementia after Alzheimer’s disease. It’s caused by damage to the network of blood vessels supplying the brain. Some symptoms are similar to those associated with Alzheimer’s and stroke, but in particular people with vascular dementia often experience difficulty thinking quickly, concentrating and communicating, as well as [read the full story…]