How do our genes affect our risk of suicidal thoughts and behaviours in childhood?

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A group of UCL masters students consider a JAMA Psychiatry study which looks at the associations between genetic risk for adult suicide attempt and suicidal behaviours in young children in the United States.

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Psychedelics-assisted psychotherapy for alcohol use disorder: room for more evidence

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In her debut blog, Heidi Stevens reviews a recent US randomised controlled trial on psilocybin-assisted psychotherapy for adults with alcohol use disorder, which leaves us with more questions than answers.

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Psychiatric Advance Directives: more effective when facilitated by peer workers, according to French RCT

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Rob Allison considers a French randomised controlled trial, which provides support for the use of peer worker–facilitated psychiatric advance directives to prevent compulsory rehospitalisation in people with severe mental illness.

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Cerebrospinal fluid biomarkers for depression

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In her debut blog, Éimear Foley reviews a recent meta-analysis that identifies possible differences between people experiencing depression and healthy controls.

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Extreme ambient heat linked to increased mental health emergencies, according to new US nationwide study

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Trish Darcy and Peter Coventry consider a novel US research study on climate change, ambient heat, and the links to increased mental health-related emergency visits.

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Borderline personality disorder criteria and suicidality

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Steven Macdonald-Hart summarises a 10-year follow-up study from the US, which measures the relationship between borderline personality disorder and suicide attempts.

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Stratified care versus stepped care for depression: which is more effective?

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Sarah Watts reviews a cluster randomised clinical trial investigating the effectiveness of stratified care compared to stepped care for depression, which has implications for IAPT services.

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Psychotherapy and antidepressant tapering can help people at risk of depression relapse, but more evidence needed before we can provide personalised treatment

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Jessica Scaife reviews a individual patient data meta-analysis exploring the continuation of antidepressants versus sequential psychological interventions to prevent relapse in depression.

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Opioid Agonist Treatment associated with 50% lower risk of mortality, but political epiphany still needed to reduce drug-related deaths

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Ian Hamilton appraises a systematic review and meta-analysis on the association of opioid agonist treatment with all-cause mortality and specific causes of death among people with opioid dependence.

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Death from COVID-19: should we be prioritising people with schizophrenia for vaccination?

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In her debut blog, Aneta Zarska reviews a cohort study which looks at the links between death from COVID-19 and a range of mental health conditions, including schizophrenia, depression and anxiety.

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