Patterns of inflammation in childhood and mental and cardiometabolic disorders in adulthood: mapping the trajectories

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Ruby Tsang summarises a recent longitudinal study of trajectories of inflammation in youth and risk of mental and cardiometabolic disorders in adulthood, which finds that high levels of inflammation in childhood may be linked to an increased risk of psychosis, depression and insulin resistance in early adulthood.

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Not all people who make a suicide attempt have a psychiatric diagnosis

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In her debut blog, Emma Wallace explores a recent US cross-sectional study, which suggests an exclusive focus on the mental health antecedents of suicide will exclude around 20% of people who attempt to take their own lives.

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The role of the gut microbiome in treatment-resistant schizophrenia

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Nuala Murray explores a recent Australian case-control study that looks at the associations between changes in gut microbiota and schizophrenia diagnosis, treatment resistance, and clozapine response.

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The many faces of mental disorders

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Yuri Milaneschi discusses new research on the structure and presentation of mental health disorders, which suggests that although there are many different faces of major mental disorders, some of these faces are far more common than others.

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Is short sleep linked to risk of psychosis and could inflammation be a factor?

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Amy Ferguson summarises a recent study published by researchers in Birmingham, which suggests that persistent shorter sleep in childhood may increase the risk of psychotic experiences.

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Cognition and heterogeneity in first-episode psychosis before antipsychotic treatment

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Ana Veic looks at an updated systematic review which suggests that patients with psychosis display cognitive difficulties very early in the disease process, and concludes this variation in cognitive function should prompt individual clinical assessments to optimise care.

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Cannabis use disorder associated with increased risk of both psychotic and nonpsychotic unipolar depression and bipolar disorder

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Jack Wilson critiques a recent Danish longitudinal study published in JAMA Psychiatry, which suggests that cannabis use disorder is independently associated with bipolar disorder and unipolar depression.

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Keep on movin’… Even small doses of physical activity can lower our risk of depression

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Elli Kypraiou considers a systematic review published in JAMA Psychiatry, which suggests that relatively small doses of physical activity were associated with substantially lower risks of depression.

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Brain-body health please: new research supports integrated physical and mental health care

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Athina Aruldass finds that management of serious neuropsychiatric disorders should acknowledge the importance of poor physical health and target restoration of both brain and body function.

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