Omega-3 supplements for the prevention of psychosis: another trial shows no benefit, so is it time to move on?

Feature

David Mongan reports on a recent trial of omega-3 supplementation for the prevention of psychosis in people at ultra-high risk, which finds no evidence of a positive effect. He reflects on these findings and considers what’s next for the field.

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Is brief text messaging effective to reduce repeat hospital-treated self-harm?

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Amelia Mullett summarises an Australian RCT on the efficacy of a short message service brief contact intervention (SMS-SOS) in reducing repetition of hospital-treated self-harm.

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Anti-inflammatory treatments for youth depression: promising but not yet implementable

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Céline Wessa reports on a recent systematic review of pharmacological anti-inflammatory treatment in children and adolescents with depressive symptoms, which has some promising results.

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Ending self-stigma: not at all straightforward

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Dave Steele summarises a recent randomised controlled trial, which suggests that there may be benefit in self-stigma programmes for those with severe mental illness, but more work is needed.

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Lived experience in suicide prevention intervention development: review of a decade’s worth of research

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Eleanor Bailey and Jo Robinson explain that most suicide prevention interventions are developed without the involvement of people who have lived experience of suicide. They go on to make a set of recommendations for how future intervention research in suicide prevention is conducted and reported.

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Caries lesions in enamel – Still drill and fill?

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This review of dental clinicians thresholds for intervention in teeth with caries included 30 studies over a 31year time span. 21% (95%CI;15%-28%) of dentists/therapists would intervene invasively for lesions confined to enamel doubling in high risk patients with little changed being noted over time.

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