Patterns of inflammation in childhood and mental and cardiometabolic disorders in adulthood: mapping the trajectories

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Ruby Tsang summarises a recent longitudinal study of trajectories of inflammation in youth and risk of mental and cardiometabolic disorders in adulthood, which finds that high levels of inflammation in childhood may be linked to an increased risk of psychosis, depression and insulin resistance in early adulthood.

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New research on metabolomic pathways supports the case to routinely screen for antenatal depression

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Nora Rosenberg summarises the largest and most comprehensive study to date on metabolomic pathways to antenatal depression, birth outcomes and offspring development.

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Inflammation and depression: new insights into sex differences in adolescents

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Sophie Fairweather explores a recent paper which suggests that the inflammatory cytokines IL-2 and IL-6 are associated with both the risk of developing depression, and with depression severity, although this relationship is modified by sex.

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Anti-inflammatory treatments for youth depression: promising but not yet implementable

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Céline Wessa reports on a recent systematic review of pharmacological anti-inflammatory treatment in children and adolescents with depressive symptoms, which has some promising results.

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Can proteomics improve our prediction of depression remission?

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Jonas Hagenberg discusses new insights into the possible use of proteomics (the large-scale study of proteins) for improving our prediction of depression remission.

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Genetic risk for schizophrenia is associated with changes in heart structure and function

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Nadine Parker and Ole Andreassen summarise a recent UK population-based cohort study, which looks at the impact of polygenic risk for schizophrenia on cardiac structure and function in over 32,000 people.

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Does what you eat affect how you feel?

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Daisy Crick summarises a recent paper on the casual relationship between polyunsaturated fatty acids and depression.

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Blood-based inflammatory markers in acute vs chronic schizophrenia

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Éimear Foley summarises a recent meta-analysis, which looks at alteration patterns of peripheral concentrations of cytokines and associated inflammatory proteins in acute and chronic stages of schizophrenia.

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Inflammation and depression in young people #ActiveIngredientsMH

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Yara Toenders and Lianne Schmaal consider the links between inflammatory dysregulation and depression in young people, by reviewing a recent study carried out by researchers in the US, and also by presenting the results of their own recent #ActiveIngredientsMH review, which was funded by the Wellcome Trust.

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Autoimmune and autoinflammatory diseases associated with higher risk of eating disorders

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Francesca Solmi appraises and summaries a recent population-based cohort study that explores the links between eating disorders and autoimmune and autoinflammatory diseases.

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