Recurrent aphthous stomatitis – topical medications

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This review of different topical medications for the management of recurrent aphthous stomatitis (RAS) included 43 RCTs. No significant differences were found for any if the treatments assessed and a majority of the included RCTs (76%) were considered to be at high risk of bias.

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Topical hyaluronic acid for recurrent aphthous stomatitis

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This review of the efficacy of topical hyaluronic acid (HA) for reducing the signs and symptoms of recurrent aphthous stomatitis (RAS) included 9 studies 8 of which were RCTs. The findings suggest that HA may be a potential treatment option for RAS but the evidence is of very low certainty.

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Interventions for oral lichen planus

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This systematic review and network meta-analysis comparing interventions for the management of oral lichen planus included 55 RCTs. While the findings suggested that topical corticosteroids may be most effective the evidence is of low to very low certainty.

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Hyaluronic acid as an adjunct to periodontal treatment

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This review looked at the adjunctive effects of hyaluronic acid (HA) on surgical or non-surgical periodontal treatment. Thirteen RCTs the majority at high risk of bias suggested that the topical application of HA may lead to additional clinical benefits.

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Temporomandibular disorders: Are intra-articular injections with platelet-rich plasma effective?

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This review of the effectiveness of intra-articular platelet-rich plasma (PRP) injections in temporomandibular disorders included only 6 low quality RCTs providing very weak evidence for a potential benefit from PRP injection.

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Antiseptic oral sprays: Do they improve oral health?

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20 RCTs involving a total of 720 patients were included in this review of antiseptic oral sprays in the control of dental plaque and gingivitis. The findings suggest then can reduce plaque levels in the short term.

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Temporomandibular joint arthrocentesis with hyaluronic acid- evidence limited.

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This review of intra-articular injections of hyaluronic acid (HA) for temporomandibular disorder only identified 8 small studies of limited quality providing no consensus that HA injections were better than other agents.

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Small study suggests positive effect for hyaluronic acid spray on swelling and trismus after third molar removal

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Postoperative pain, swelling and trismus are common postoperative problems following the removal of impacted third molars. Hyaluronic acid (HA) is a major carbohydrate component of the extracellular matrix and can be found in many tissues and has been introduced as a bio-material with potential to enhance wound healing. It has been used in ophthalmology, dermatology, [read the full story…]