What can genetics tell us about the link between cannabis and schizophrenia? #MHQT

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Suzi Gage summarises a recent GWAS of lifetime cannabis use, which reveals new risk loci, genetic overlap with psychiatric traits, and a causal influence of schizophrenia. Interesting new evidence ahead of our Mental Health Question Time #MHQT event in London tomorrow.

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Depression and anxiety: two sides of the same coin? #TransDX2018

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Ava Schulz reviews a paper by Mansell and McEvoy which looks at psychopathology in a heterogenous clinical sample of anxiety and depression.

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The genetics of depression (and anxiety!)

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Thalia Eley shares her thoughts on a recent Nature genome-wide association study of depression phenotypes in the UK Biobank, which uses different definitions of depression to provide more tractable targets for future genetic studies.

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Understanding the genetics of antipsychotic treatment response

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Marcus Munafo looks at a Chinese genome-wide association study that claims to have identified some of the genes associated with response to antipsychotic treatment.

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Risk factors and peripheral biomarkers for schizophrenia spectrum disorders

This 'umbrella review' aimed to systematically appraise the meta-analyses of observational studies on risk factors and peripheral biomarkers for schizophrenia spectrum disorders.

Marcus Munafo considers the findings of a systematic review of meta-analyses of observational studies, which looks at risk factors and peripheral biomarkers for psychotic disorders on the schizophrenia spectrum.

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Autoimmune and autoinflammatory diseases associated with higher risk of eating disorders

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Francesca Solmi appraises and summaries a recent population-based cohort study that explores the links between eating disorders and autoimmune and autoinflammatory diseases.

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Psychiatric genomics: an update and an agenda

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Marcus Munafo comments on a review of the work of the Psychiatric Genomics Consortium, which in recent years has delivered an increasing flow of new knowledge about the fundamental basis of common psychiatric disorders.

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Genetics of depression: risk factors and protective factors

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Marcus Munafò reports on a new genome-wide association study that identifies 44 risk variants and helps us to further refine the genetic architecture of major depressive disorder.

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Nicotine reverses hypofrontality in animal models of addiction and schizophrenia

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Marcus Munafo looks at a complex and sophisticated series of experiments that provide further insight into the relationships between genetic risk, cigarette smoking and schizophrenia.

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