The role of the gut microbiome in treatment-resistant schizophrenia

Feature

Nuala Murray explores a recent Australian case-control study that looks at the associations between changes in gut microbiota and schizophrenia diagnosis, treatment resistance, and clozapine response.

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Shorter sleep and depression: what role do our genes play?

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Nick Donnelly discusses how one’s genetic predisposition to shorter sleep is associated with the onset of depression in older adults.

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Can proteomics improve our prediction of depression remission?

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Jonas Hagenberg discusses new insights into the possible use of proteomics (the large-scale study of proteins) for improving our prediction of depression remission.

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Genetic risk for Tourette Syndrome and related conditions

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Ed Palmer considers new research on the genetic risk for Tourette Syndrome and it’s relationship to other mental and physical health conditions.

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Dental caries and genetics – is there a link?

Twins

This review assessing the agreement of dental caries experience between monozygotic (MZ) and dizygotic twins (DZ) included 19 studies. While the findings indcate a possible a genetic influence the certainty of evidence is very low so the findings should be interpreted very cautiously.

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Genetic risk for schizophrenia is associated with changes in heart structure and function

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Nadine Parker and Ole Andreassen summarise a recent UK population-based cohort study, which looks at the impact of polygenic risk for schizophrenia on cardiac structure and function in over 32,000 people.

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How do our genes affect our risk of suicidal thoughts and behaviours in childhood?

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A group of UCL masters students consider a JAMA Psychiatry study which looks at the associations between genetic risk for adult suicide attempt and suicidal behaviours in young children in the United States.

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Does what you eat affect how you feel?

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Daisy Crick summarises a recent paper on the casual relationship between polyunsaturated fatty acids and depression.

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Cannabis use in college: genetic predispositions less influential than social environment

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Sally Turner reviews a recent study exploring cannabis use in college, which provides useful evidence relating to how universities could promote a sense of community, belonging and support to students who use cannabis.

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Loneliness “from the outside”: how are lonely young people perceived by others?

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In her debut blog, Phoebe McKenna-Plumley explores a mixed methods study of young people, which finds concordance between self-reported loneliness and others’ perceptions of loneliness.

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