This review of the effectiveness of chlorhexidine mouthwash with an anti-discoloration system (ADS) is effective in preventing extrinsic tooth surface discoloration included 13 RCTs with the findings suggesting that ADS reduces staining but did not affect its properties with respect to gingival inflammation and plaque scores.
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This Cochrane review update of the effects of home-based tooth whitening products dispensed by a dentist or over-the-counter included 71 RCTs. However, most of thetrials were small single studies of interventions of highly variable nature providing very low-certainty evidence over short time periods to support the effectiveness of home-based chemically-induced whitening.
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This review of the effect of whitening toothpastes on tooth staining included 21 RCTs and found a significant effect on all aspects of staining in the short term.
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