This review of the use of oral appliances for the treatment of obstructive sleep apnoea identified 17 trials, all but one of which wере randomised. The results suggest significant benefits in respiration and sleep quality, compared to placebo devices or blank control.
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Obstructive sleep apnoea-hypopnoea (OSAH) affects 2-7% of adults. This trial compared 3 mandibular advancement devices with no treatment for mild disease and found benefits over the short term for a range of outcomes including Apnoea-Hypopnoea Index, the Epworth Sleepiness Scale and cost-effectiveness.
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