Salivary biomarkers for diagnosing periodontal disease

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This review of salivary biomarkers for diagnosing periodontal disease only identified 4 studies at high risk of bias but suggests a small number of potential biomarkers. However the findings should be interpreted with caution.

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Prognosis of brief psychotic episodes

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Samei Huda presents the findings of a new meta-analysis, which explores the prognostic significance of competing ways of defining and measuring brief psychotic episodes.

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Is it bipolar disorder or borderline personality disorder?

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Murtada Alsaif considers the challenges facing psychiatrists in diagnosing bipolar disorder or borderline personality disorder. He reports on a recent qualitative study that explores the practical experience of psychiatrists and nurses and concludes that clinical diagnostic practice cannot reliably distinguish the two conditions.

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Improving diagnosis of bipolar disorder: can blood-based diagnostic panels help?

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Can blood-based diagnostic panels help us reduce the misdiagnosis and inappropriate treatment often experienced by people with bipolar disorder? Murtada Alsaif reviews a recent retrospective study that has some encouraging findings for biologically identifying the disease.

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Population screening for dementia

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Rosalyn Nelson reports on a recent systematic review about population screening for dementia, which highlights the negative attitudes of patients, carers and health care professionals towards screening. She asks: what are the risks of ignoring diagnosis?

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Caries detection: visual detection has good accuracy

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This review included 102 studies the majority (77%) being laboratory-based findings that visual inspection had good caries detection accuracy in primary and permanent teeth, with a trend for higher specificity than sensitivity.

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Oral Cancer diagnosis: biopsy and histology still best method

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This Cochrane review of adjunctive diagnostic tests for oral cancer included 41 studies assessing vital staining, cytology, and light-based tests. The available studies were of poor quality detection with none of the tests being considered as a replacement for the currently used standard of a scalpel biopsy and histological assessment.

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The Rowland Universal Dementia Assessment Scale is a good tool for diagnosing dementia in multicultural populations

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Clarissa Giebel summarises a systematic review, which concludes that the Rowland Universal Dementia Assessment Scale (RUDAS) has good sensitivity (77.2%) and specificity (85.9%) for diagnosing dementia in multicultural populations.

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Personality disorder: time for more attention and debate

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Andrew Shepherd summarises a recent series of papers in The Lancet which look at the latest research on personality disorders. This includes evidence on classification, prevalence, diagnosis, treatment and the experience of personality disorder across the life course.

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A multitude of systematic reviews on dementia diagnosis

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Clarissa Giebel highlights 5 new Cochrane reviews on dementia diagnosis, focusing on the Mini-Cog, IQCODE and MMSE diagnostic tests.

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