Citalopram outperforms all other antidepressants except escitalopram for acute phase depression, according to new review

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Citalopram (brand names: Cipramil and Celexa) is an antidepressant drug in the selective serotonin reuptake inhibitor (SSRI) class. It was one of the first SSRIs to come onto the market over 20 years ago and is available as tablets and as oral drops that are taken in a juice drink. There are lots of antidepressants [read the full story…]

Women who work long hours are at risk of depression and anxiety

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It seems logical that people who work long hours and have a stressful job are more likely to suffer from depression, yet epidemiological studies that have investigated the links between long working hours and depression have reported inconsistent findings. The Whitehall II prospective cohort study followed nearly 3,000 British staff from across 20 civil service [read the full story…]

New Cochrane review shows that exercise helps with depression, but more research is needed

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This is perfect timing from the chaps at the Cochrane Depression, Anxiety and Neurosis Group. After all the hubbub about exercise and depression a few weeks ago, it’s great to read an updated version of their systematic review that looks at the effectiveness of exercise in the treatment of depression. The review looked for randomised [read the full story…]

Insufficient evidence for low-intensity interventions to prevent depression relapse or recurrence

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Anyone who has ever been depressed knows that there is always a chance that the condition may return. We know that the more episodes of depression an individual has, the more likely they are to have further episodes, so it’s vital that we do all that we can to prevent relapse after depression. This feeling was [read the full story…]

Mindfulness-based stress reduction programmes help reduce anxiety, depression and stress

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Mindfulness has become a popular self-management technique to relieve stress and cope with busy day-to-day lifestyles. This review defines mindfulness as the ability to “non-judgementally observe sensations, thoughts, emotions and the environment, while encouraging openness, curiosity and acceptance”. It looks specifically at a technique called Mindfulness-Based Stress Reduction (MBSR) programmes, which is a training programme [read the full story…]

New Dutch guideline seeks to reduce unnecessary prescribing of antidepressants to people with depressive symptoms

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I don’t normally blog about non-English language publications, but this new evidence-based guideline from the Dutch College of General Practitioners caught my eye yesterday. The guidance says that antidepressants should only be given as a first line treatment to people with severe depression and that those who only have depressive symptoms should be given a [read the full story…]

Here is the evidence for exercising if you are depressed

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Ooh, what a palaver over the depression and exercise story!  Such a lot of words have been written about the study published in the BMJ last week, including by me. The study itself was well conducted but frankly disappointing (for us readers and the researchers themselves), finding as it did that a specific treatment to [read the full story…]

‘Exercise doesn’t help with depression’ – have the headline writers got it wrong again?

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Back from my 5-mile run around the woodland yesterday morning I sat down to catch up on the latest elf stories. Many of the national newspapers reported on a new randomised controlled trial published in the BMJ, which studied ‘facilitated physical activity’ for people with depression. The headlines seemed to be in agreement: Exercise ‘no [read the full story…]

Premature babies have greater risk of serious mental illness

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Preterm babies are three times more likely to be admitted to hospital for a mental health problem as an adult than normal term babies, according to a study published in the Archives of General Psychiatry by researchers in the UK and Sweden. About 1 in every 13 children born in the UK are classified as [read the full story…]

New long term conditions compendium from the Department of Health

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Commissioners, health professionals and social care professionals will all be interested in the new Long Term Conditions Compendium of Information published by the Department of Health. This third edition updates the version produced in 2008 and provides the evidence for improving care and outcomes for people with long-term conditions. 70% of the total health and [read the full story…]