Meta analysis of antidepressants vs talking therapies: another example of ‘All Must Have Prizes’?

Depression

Patients presenting to their GP with a mental health problem are likely to be offered medication, in the form of antidepressants, and/or a ‘talking therapy’, such as counselling or CBT. This is because we know that both those broad categories of treatments (drugs and psychological therapies) are effective in reducing symptoms. However, it’s less clear [read the full story…]

Systematic review finds that tricyclics do not benefit children with depression

A girl

Clinical depression is one of the most common mental health problems occurring in children and adolescents. It is often accompanied or followed by additional negative outcomes, including social and academic problems, anxiety and substance use. Many depressed adolescents continue to have recurring problems throughout adulthood. A variety of antidepressant drugs, such as tricyclics and selective [read the full story…]

Post-ACS depression treatment more effective when led by patient preference

The role of patient choice was a critical component of this study

Patients who suffer from depression after acute coronary syndrome (ACS) may benefit from stepped treatment, which takes patient preference into account, a recent study suggests. Furthermore this course of action does not appear to result in a significant increase in healthcare costs. Crucially post-ACS depression has been associated with both an increased risk of ACS [read the full story…]

The magnificent 7? Review finds that different “talking therapies” offer similar benefits to people with depression

Talking

Scientific studies comparing treatments for depression and depressive disorders keep the mental elves very busy. Most months we are asked to blog on about 3 newly published reviews on this hot topic. The interest in research on the treatment of depression comes as no surprise, when one considers that depressive disorders affect a staggering one-fifth [read the full story…]

Systematic review shows higher quality RCTs needed on psychological effects of exercise for type 2 diabetes

shutterstock_114580729 (1)

In the UK alone it’s estimated over two million adults have type 2 diabetes. That clearly warrants some serious research into its prevention and treatment, including the valuable role of exercise.  We also know the effects of diabetes are not confined to physical problems, linked as it is to reduced quality of life as well [read the full story…]

Transcranial magnetic stimulation (rTMS) enhances response to antidepressants: a rather flawed meta-analysis

An image of a brain

It’s a well-known fact that elves are allergic to unhappiness, so the fact that there are at least 350 million sufferers of depression worldwide1 is quite a problem. That’s before we’ve even mentioned the crippling mortality, morbidity and economic impact that depression causes. The trouble is, our treatments for depression aren’t perfect. Less than a [read the full story…]

Treatment of depression after a heart attack does not improve the long-term risk of adverse cardiac events but may increase survival

shutterstock_heart and doctor

Although there have been huge advances in the treatment of heart disease, it is still the UK’s biggest killer (more information on heart disease can be found at the British Heart Foundation’s website). Depression after a heart attack is common (roughly 20% prevalence) and can worsen heart disease and increase the risk of death.  A [read the full story…]

More frequent psychotherapy may lead to better depression outcomes, says new meta-analysis

Calendar

Psychological therapies such as cognitive behaviour therapy, interpersonal psychotherapy, behavioural activation, problem-solving and possibly psychodynamic therapy have been clearly shown to be effective in the treatment of adult depression. However it is not clear, how long such a therapy should last, how many sessions are optimal and what the best intensity of psychotherapy is. A [read the full story…]

Talking therapy for teenagers (MBT-A) reduces self-harm and depression in self harming teens over a 12 month period

Young people skateboarding

In adults there is a growing body of evidence for psychotherapeutic interventions such as Transference Focussed Psychotherapy, Mentalization-Based Treatment and Dialectic Behavioural Therapy for patients who self harm. In the teenage population, there has been limited evidence to show that interventions are better than the treatment already provided. MBT has developed from psychodynamic psychotherapy and [read the full story…]

Computerised CBT is effective for depression in the short-term, but new meta-analysis suggests no long-term functional improvement

Help button on a computer keyboard

Studies have demonstrated that CBT works at least as well as antidepressants at reducing depression, perhaps even better (DeRubeis et al., 1999). However, it’s difficult for people with depression to access CBT due to lengthy waiting lists. The Improving Access to Psychological Therapies (IAPT) scheme has had a major influence on waiting times for people [read the full story…]