Do smoking cessation treatments increase the risk of depression and suicide?

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Smoking is a major preventable cause of morbidity and premature mortality throughout the world. There are an estimated 460,000 hospital admissions attributable to smoking in people aged over 35 every year, with an average annual cost to the NHS of £2.7 billion. Many strategies exist to help people give up smoking. The most common are [read the full story…]

Varenicline, smoking cessation and neuropsychiatric adverse events

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Varenicline is a prescription drug to help people stop smoking that works by stimulating the nicotine receptors in the brain to reduce cravings and decrease the pleasure that results from smoking. Quit attempts aided by varenicline are up to 2-3 times more successful than those without (Cahill et al 2009 and 2012). However, following the [read the full story…]

Counselling is as effective as CBT for depression, according to a reanalysis of RCT data

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In recent years, cognitive-behavioural therapy (CBT) has become the most widely delivered therapy for depression within the NHS.  CBT interventions are recommended by NICE for people with mild, moderate and severe depression. By contrast, recent NICE guidelines recommend counselling only for people with persistent subthreshold depressive symptoms or mild to moderate depression who decline another [read the full story…]

Expert review suggests that school-based depression and anxiety prevention programmes are effective in the short term

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It is estimated that 20% of children up to the age of 18 will have suffered an emotional disorder of depression or anxiety (Costello et al., 2003). These two mental health conditions commonly occur together and can significantly influence daily functioning, relationships and education in this age group. Effective and evidence-based psychological treatments have been [read the full story…]

Treating antenatal depression could prevent offspring adult depression

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Depression in late adolescence is a major public health concern, not least because it is strongly predictive of persistent, adult depression, which can have a severe effect on socioemotional functioning, education and employment. Increasingly, depression research is turning its attention to the matter of prevention of depression rather than exclusively focusing on treatment options and [read the full story…]

Largest RCT so far suggests that ketamine may be useful in the acute treatment of refractory depression

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Major depression is a serious mental illness that often does not respond to mainstream drug treatment (antidepressants). In addition, there is usually a delay of 2-6 weeks before mood improves significantly. In situations like this, when at least two conventional antidepressants have been tried without success, depression is considered treatment-resistant. While multiple different strategies to [read the full story…]

Better together: how collaborative working can improve outcomes for patients with depression and diabetes

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The link between depression and diabetes mellitus (DM) is well established. Around 20% of patients with DM meet diagnostic criteria for depression. The National Institute for Health and Care Excellence (NICE) issued guidance impressing the importance of diagnosing and treating depression in long-term conditions such as DM (NICE, 2009). However, depression in the presence of [read the full story…]

Mood management can improve smoking cessation in patients with past and current depression

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There is a high rate of co-morbidity between depression and smoking; rates of smoking are approximately double in those with depression compared with the general population. In addition, smokers with depression tend to have higher rates of nicotine dependence, suffer greater negative affect during abstinence/withdrawal, are more likely to fail in quit attempts, and are [read the full story…]

Systematic review highlights a lack of evidence about using antidepressants to treat cancer patients with depression

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Having a life threatening disease such as cancer and undergoing gruelling treatment can have detrimental psychological effects. According to a recent review, for instance, the prevalence of depression among cancer patients is 10.8%, when assessed by a standardised clinical assessment (Ng et al. 2011). The authors of this meta-analysis make the argument that established criteria [read the full story…]

Review finds weak link between cannabis use and increased risk of developing depression

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Cannabis is the second most commonly used recreational drug, after alcohol, in the UK. The number of regular users has risen considerably over the past decade, and this has been particularly apparent in the adolescent population. With this rise there have been concerns about the long term consequences of heavy cannabis use. Cannabis use has [read the full story…]