Sophie Fairweather explores a recent paper which suggests that the inflammatory cytokines IL-2 and IL-6 are associated with both the risk of developing depression, and with depression severity, although this relationship is modified by sex.
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Nick Donnelly discusses how one’s genetic predisposition to shorter sleep is associated with the onset of depression in older adults.
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Andrea Cipriani is back, this time writing with Rosario Aronica to summarise an individual patient data meta-analysis on the use of psychological interventions for preventing relapse in depression.
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Elli Kypraiou considers a systematic review published in JAMA Psychiatry, which suggests that relatively small doses of physical activity were associated with substantially lower risks of depression.
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Paris Lalousis reviews a recent study that looks into the differences in brain connectivity between males and females, which suggests a potential sex-based divergence in the neurobiological underpinnings of psychiatric disorders.
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Lisa Lloyd and Krupa Sheth summarise a study investigating the role of racism and trauma on the intergenerational transmission of depression between Black mothers and their children.
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Céline Wessa reports on a recent systematic review of pharmacological anti-inflammatory treatment in children and adolescents with depressive symptoms, which has some promising results.
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In her debut blog, Asha Ladwa discusses a secondary analysis of data from the ANTLER trial, which investigated the clinical factors associated with relapse in primary care patients on long-term maintenance antidepressants.
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Aslihan Baser summarises a systematic review and meta-analysis investigating the risk for developing anxiety disorders in children whose parents experience mood disorders.
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Athina Aruldass finds that management of serious neuropsychiatric disorders should acknowledge the importance of poor physical health and target restoration of both brain and body function.
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