How can psychedelics treat mental illness? #PsilocybinMedicine

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Catherine Bird writes her debut elf blog on a recent opinion review by Robin Carhart-Harris entitled: How do psychedelics work?

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How can we prevent depression in young adults?

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Mental Health Masters Students from UCL explore a recent systematic review and meta-analysis of interventions to prevent depression in young adults. The review finds some evidence for the effectiveness of preventative interventions in reducing depressive symptoms in young adults, but the evidence in this area remains weak.

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Genetic predictors of depression trajectories in adolescence

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Megan Skelton explores a study that uses polygenic scores in the context of longitudinal developmental data, to characterise developmental trajectories and the role of neuropsychiatric genetic risk variants in early-onset depression.

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A psychological victory for the domestic violence and abuse sector: the PATH trial

Young adults who reported depressive and/or suicidality symptoms in adolescence were significantly more likely to have experienced relationship violence in their romantic relationships

Emma Yapp summarises two new studies out yesterday looking at the PATH intervention (Psychological Advocacy Towards Healing), a CBT-informed psychological intervention delivered by trained domestic violence and abuse (DVA) advocates in specialist services.

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Genetics of depression: understanding risk and improving treatment

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Douglas Levinson on a genome-wide meta-analysis of depression in 807,553 individuals, which identifies 102 independent variants relating to the genetics of depression.

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Do you have my back? Perceived social support, loneliness, and its impact on mental health outcomes

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In the lead up to our Loneliness Mental Health Question Time on 3rd Dec 2018, Dr Michelle Lim summarises a recent systematic review on the associations between loneliness and perceived social support and outcomes of mental health problems.

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Sense of coherence and mental health of caregivers: a systematic review and meta-analysis

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Martin Webber looks at a systematic review and meta-analysis of studies reporting on the association between informal carers’ sense of coherence, caregiver burden and mental health outcomes.

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The impact of facial scarring: routinely assess for affective distress

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Andrew Thompson writes his debut blog on a recent systematic review that explores the associations linking facial scarring (largely caused by assaults or burn injuries) to depression and anxiety.

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Improving antidepressant outcomes: what works for whom and why?

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Thalia Eley and Gerome Breen explore a new systematic meta-review of predictors of antidepressant treatment outcome in depression, which looks at clinical and demographic variables, but also biomarkers including both genetic and neuroimaging data.

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