Maintenance or discontinuation of antidepressants for depression? Findings from the ANTLER trial

For every 6 people stopping their medication there was one additional relapse compared to those who maintained their antidepressant treatment, suggesting that stopping medication has an increased risk of relapse.

Raphael Rifkin-Zybutz and Sameer Jauhar summarise the recently published ANTLER trial, which explores whether antidepressant maintenance can reduce the risk of relapse in depression.

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Disordered eating during COVID: understanding experiences from Reddit posts

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Georgie Parker summarises a research study of Reddit comments posted during Covid-19, which looks at how the pandemic and lockdown affected people with disordered eating behaviours.

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Male suicide prevention: uncovering the challenges associated with “talking”

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Cara Richardson explores a recent qualitative study conducted in Scotland, which finds that the contexts in which men talk about suicide are an important part of male suicide prevention.

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Deep brain stimulation for severe depression: could ‘brain pacemakers’ be the answer for some?

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Alexandra Pike, Alexis An Yee Low and Jonathan Roiser critically appraise a recent n-of-1 study on ‘brain pacemakers for depression’, which received extensive press coverage earlier this month. The case study looks at deep brain stimulation (closed-loop neuromodulation) in an individual with treatment-resistant depression.

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CBT for youth anxiety and depression: satisfaction guaranteed?

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Alice Potter explores a systematic review which finds that children and young people are often satisfied with the CBT (cognitive behavioural therapy) they receive for anxiety or depression.

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Are we Improving Access to Psychological Treatment for everyone?

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Bibire Baykeens reviews a general population cohort study which suggests that recent migrants are less likely to use the Improving Access to Psychological Treatment programme.

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Misdiagnosis or missed diagnosis? What are the potential implications for undiagnosed autistic people?

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Rachel Symons reviews a recent Italian study which finds that autism spectrum disorder is still commonly undiagnosed and misdiagnosed in adults.

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Age at onset of mental disorders: global meta-analysis provides data for targeting effective interventions

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Dona Matthews summarises a comprehensive global meta-analysis that presents our best current knowledge on the age of onset of various mental disorders. This review has major implications for our mental health promotion and prevention efforts.

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School-based mental health interventions: reducing depression, anxiety and aggressive behaviour

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In their debut blog, Rasanat Fatima Nawaz and Lauren Cross summarise a comprehensive review from the Early Intervention Foundation on school-based mental health interventions.

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Psychotherapy and antidepressant tapering can help people at risk of depression relapse, but more evidence needed before we can provide personalised treatment

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Jessica Scaife reviews a individual patient data meta-analysis exploring the continuation of antidepressants versus sequential psychological interventions to prevent relapse in depression.

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