Hormonal coil dosage and depression risk

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Dr Rachel Reid-McCann discusses the latest research on dosage of levonorgestrel-releasing intrauterine system (LNG-IUS) and the risk of depression. A well conducted study from Denmark “provides evidence of a dose-dependent association between LNG exposure and risk of subsequent depression across three dosages”.

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Childhood adversity and adult depression: Psychoanalysis vs CBT

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Ella Tuominen looks at a study of childhood adversity and ‘treatment resistant depression’ and asks: Can long-term psychoanalytic therapy provide deeper healing for chronic depression than CBT?

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Home-based brain stimulation (tDCS) for depression: ready for widespread use?

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Julian Mutz discusses the results of a new 10-week RCT assessing home-based brain stimulation for depression, which suggests that tDCS may be a safe, acceptable and efficacious treatment for moderate depression.

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Treatment of harmful gambling in the UK: new review highlights worrying lack of evidence

Developing evidence-based interventions for gambling-related harms would help improve the effectiveness of care across under-recognised populations. 

Clare Gerada and Ruby Wiltshire summarise a new scoping review of UK-based research on the treatment of harmful gambling, which finds a complete lack of high quality intervention studies to support decision making.

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The genetic relationship between ADHD and depression

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Tim van der Es discusses a recent paper that investigates whether ADHD causally increases the risk of subsequent major depression diagnoses. The study findings underscore the need for effective treatment and assessment of ADHD and a requirement for a deeper understanding of the potential causal mechanisms linking ADHD and depression.

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Patterns of inflammation in childhood and mental and cardiometabolic disorders in adulthood: mapping the trajectories

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Ruby Tsang summarises a recent longitudinal study of trajectories of inflammation in youth and risk of mental and cardiometabolic disorders in adulthood, which finds that high levels of inflammation in childhood may be linked to an increased risk of psychosis, depression and insulin resistance in early adulthood.

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Critical lack of evidence about social media use and youth mental health in clinical populations

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Amanda Sabo and Louise La Sala summarise a recent review investigating the impact of social media use on internalising symptoms in adolescents from clinical and community samples.

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Will this ADHD medication help my patient? Bridging the gap between efficacy and effectiveness

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Shuichi Suetani blogs a new study published today in The Lancet Psychiatry, which suggests that those patients who might benefit most from evidence-based guidance are the least represented in clinical trials about ADHD medication. Is it time to reconsider the value we place on RCTs when they do not include the vast majority of people who need help?

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Like father like offspring: paternal anxiety associated with children’s emotional and behavioural health

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Zoe Firth summarises a recent systematic review which finds that anxiety in fathers has a broadly similar impact on children, compared to maternal anxiety.

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Omega-3 supplements for the prevention of psychosis: another trial shows no benefit, so is it time to move on?

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David Mongan reports on a recent trial of omega-3 supplementation for the prevention of psychosis in people at ultra-high risk, which finds no evidence of a positive effect. He reflects on these findings and considers what’s next for the field.

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