This review of different surgical treatments for odontogenic keratocsysts (OKC) with respect to recurrence rates includes 40 observational studies. The finding suggest that enucleation plus peripheral ostectomy/curettage and 5-Fluorouracil had the lowest recurrence rate and enucleation alone the highest but the evidence is mainly of very low certainty.
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This review of the efficacy and safety of topical interventions used for recurrent aphthous stomatitis included 72 studies assessing 29 different interventions. Most of the interventions did not demonstrate significant differences with limitednumbers of studies for some interventions and overal limitations in the quality of the evidence.
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This review of the effect of intracanal cryotherapy in reducing postoperative pain after instrumentation or obturation in root canal treatment included 8 RCTs. The findings suggest that suggests that intracanal cryotherapy in the form of cold saline irrigation as the final irrigant significantly reduces pain between 6 and 24 hours after root canal therapy.
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This review of surgical approaches for keratocystic odontogenic tumour identified 35 mainly retrospective studies. Radical resection had the lowest recurrence rate but has significant morbidity. Higher quality evidence is to clarify the evidence for the varying surgical approaches.
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This review of postoperative hilothrarpy (cryotherapy) in facial surgery included 6 RCTs none of which were at low risk of bias. The findings suggest that it reduces swelling and pain in the early postoperative period. However more high quality studies from a broader range of researches are needed to confirm the findings.
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While there are a number of reviews of treatment options for the keratocystic odontogenic tumour (KCOT), this update of a Cochrane review could identify no relevant RCTs of treatment options. So there is a clear need for well designed and conducted randomised controlled trials to evaluate treatments for KCOTs.
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5 studies were included in this review of hilotherapy. While the studies suggest that hilotherapy might provide patients with a significant reduction in postoperative facial pain and oedema, the quality of the studies is low.
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Osteoarthritis of the knee is a common condition and typically presents with painful and restricted function and sometimes varus (bow legs) and valgus (knock knees) deformity of the knee. Once the condition and pain worsens knee joint replacement surgery is a treatment option. Patients typically improve in terms of pain and function but there is [read the full story…]
