Do folic acid supplements in pregnancy prevent autism in children? A new cohort study suggests there is a link but more evidence is needed

Pregnant belly

For many mums-to-be it is advised that taking regular folic acid supplements during pregnancy, and whilst trying to conceive, has significant health benefits for their unborn baby, namely around reducing the risk of neural tube defects such as spina bifida (NHS, 2013). However, do these supplements also affect the risk of the unborn baby developing [read the full story…]

Daily psychological demands are associated with progression of carotid artery atherosclerosis

National Heart Month

As the British Heart Foundation National Heart Month draws to a close Lifestyle Elf and I were discussing their blog on heart attacks not being reduced in people taking vitamins and antioxidants which led to us to thinking about the relationship between stress and cardiovascular disease (CVD). Our colleagues in the Pittsburgh Health Heart Project [read the full story…]

People with schizophrenia are significantly more likely to die from heart disease and cancer

Unequal measures

Since starting this blog two years ago, I have written about a number of studies that highlight the health inequalities faced by people with severe mental illness. The evidence keeps piling up and it’s really quite shocking that we are not doing more to diagnose and treat physical health problems in people with conditions such [read the full story…]

SSRI use in pregnancy does not increase the risk of stillbirth, neonatal mortality or post-neonatal mortality

Newborn baby and mother

Studies have shown that the prevalence of depression in pregnant women is 7-19%. Being depressed during pregnancy can result in preterm delivery, which can in turn lead to illness and even death of the newborn child. Researchers have struggled to single out the causes of these risks. Is it the depression, the medical treatment being [read the full story…]

More potassium, calcium and magnesium in the diet, reduces the risk of vascular dementia

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Dementia is a huge issue. As our population ages, the incidence of the disease is on the increase and attempts to prevent and treat the condition with drugs have not been as successful as we hoped. A lot of effort has gone into investigating ways in which lifestyle factors such as diet can impact on [read the full story…]

Risk factors for suicide and accidental death. What can we learn from last episodes of self-harm?

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Self-destructive behaviour is often brought on by mental illness, poverty and other life problems. As individuals spiral down they sometimes come into contact with health and social care services. This may be a primary care visit, emergency treatment in hospital or simple cries for help to friends and family. Hindsight would show us that a [read the full story…]

Antidepressants and suicide risk: retrospective cohort study reports cautious findings

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Research has shown that antidepressant use can lead to a non-significant increase in the risk of suicidal thoughts and behaviour in people aged under 25 (Stone et al, BMJ 2009). This subject rightly received a large amount of media coverage a few years ago and it remains an area where new studies can add to [read the full story…]

Genetic tests unlikely to help improve drug treatment for depression, according to new cohort study

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There has been a lot of discussion over recent years about the ways in which genetic testing may help make the treatment of depression become more targeted and effective. The theory is that genetic markers may help predict how different people are likely to respond to different drugs. This is clearly something that would interest [read the full story…]

Benzodiazepines and dementia risk: another reason to caution against long-term use

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Benzodiazepines are an effective treatment for acute anxiety and transient insomnia, but guidelines advise that they should not be prescribed for longer than a few weeks as their long-term use can lead to dependency and falls in older people (amongst other things). The evidence appears compelling and yet benzodiazepines are still widely prescribed in the [read the full story…]

Can ADHD symptoms help predict early-onset substance use?

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The relationship between attention-deficit hyperactivity disorder (ADHD) and substance use in children is hotly debated. ADHD symptoms include inattention, hyperactivity/impulsivity and conduct disorders, and there’s considerable interest in finding out which of these predicts early substance use. If we have reliable evidence that answers this question we can make informed decisions about treating ADHD and [read the full story…]