Cohort study links early exposure to intimate partner violence with poor mental health outcomes, but longer follow-up is needed

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Negative childhood experiences have always been a big topic in psychology and psychiatry, as they tend to be associated with poor mental health outcomes in later life. Intimate partner violence (IPV) harms not only the adults directly involved in it, but also the children – witnessing IPV as a child is a known risk factor [read the full story…]

Suicidal ideation and behaviour may increase when adolescents are exposed to schoolmate and personally known suicides

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Suicidal ideation and behaviours are widespread and serious amongst adolescents (Husky et al., 2012). One theory suggests that suicide in this age group is caused by ‘suicide contagion’ (exposure to a suicide may influence an individual to attempt suicide). Ecological studies have indeed demonstrated this and show that suicide rates increase following a highly publicised [read the full story…]

Are psychotic symptoms predictive of suicide attempts?

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Over the past several years, there has been a lively academic debate about what it means to have psychotic symptoms. Although these symptoms (most commonly auditory hallucinations) can be part of the expression of a psychotic illness, on their own they are neither necessary nor sufficient for a diagnosis. In fact, researchers from many countries [read the full story…]

Psychiatric comorbidity increases the risk of premature mortality in epilepsy

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There is a back to school feeling in the air in the Woodland this week, and so this comes to you with the help of my shiny new yellow pencil case. Epilepsy affects around 70 million people around the world and premature mortality is substantial with almost half of epilepsy-related deaths occuring in those younger [read the full story…]

It’s not the combat, maybe it’s the drinking in vulnerable young men

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A cohort study published in JAMA tried to answer the question what are the risk factors for suicide in the US military. This is a hot topic as the rate of suicide has increased in US military personnel from about 11/100,000 people in 2005 to about 18/100,000 so that now deaths from suicide outnumber deaths [read the full story…]

Tricyclic antidepressants are associated with higher risk of bone fracture

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While most people would likely associate tricyclic antidepressants (TCAs) with more common adverse effects such as dry mouth, sedation and constipation, there is some evidence to suggest increased occurrence of bone fractures (Vestergaard, Rejnmark, & Mosekilde, 2006). However, the topic remains controversial and conflicting results about the association of TCAs and fracture risk abound (e.g. [read the full story…]

Mortality rates amongst drug users in relation to time after hospital discharge

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People with substance misuse problems often present to services with complex physical and mental health needs.  Studies in the UK have indicated that common mental health problems are the norm in people in treatment for substance misuse. Weaver et al (2003) found 70% of people in treatment for substance misuse in London also had a [read the full story…]

Foetal exposure to sodium valproate is linked with autism risk

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The risks of congenital malformations and impact of cognitive development after foetal exposure to anti-epileptic drugs has been known for some time. Sodium valproate is a frequently used drug for epilepsy and other disorders (including bipolar disorder and migraine). The researchers aimed to examine the link between foetal exposure and subsequent development of autism. Methods [read the full story…]

Inappropriate use of antipsychotics to treat behavioural and psychological symptoms of dementia is likely to be more prevalent in care homes and low-income households

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Antipsychotics were discovered as an effective treatment for schizophrenia in the 1950s, but their use was expanded despite lack of supporting evidence, to treat other patient groups.  This included treating aggression, agitation and other behavioural and psychological symptoms of dementia (BPSD). There is evidence that these distressing symptoms can often be prevented or managed without [read the full story…]

The cardiovascular safety of dementia medications: a cross national study

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Two of the most widely available medicines for dementia in the UK are cholinesterase inhibitors and a N-methyl-D-aspartate (NMDA) receptor antagonists (NHS, 2013).  Both drugs are popular because they have been found to lead to improvements in dementia symptoms (Raina 2008). However, some have raised concerns about the safety for patients. These concerns are partly [read the full story…]