Substance misuse and addiction in people with intellectual and developmental disabilities

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Andrew Jones summarises a recent Canadian cohort study, which explores the extent of substance misuse and addictive disorders among adults with intellectual and developmental disabilities.

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OCD risk may increase following perinatal complications

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Alan Underwood summarises a population based cohort study of 2.4 million Swedish children, which highlights links between perinatal risk factors such as smoking during pregnancy, and later development of obsessive compulsive disorder.

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Antipsychotic efficacy measured by real-world observational study

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Tracey Roberts examines whether a retrospective observational study accurately investigates the effectiveness of second and first generation antipsychotics.

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Childhood traumatic brain injuries predict risk of poor long-term outcomes

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Eleanor Kennedy reports on a nationwide Swedish cohort study, which finds that traumatic brain injury consistently predicted later risk of premature mortality, psychiatric inpatient admission, psychiatric outpatient visits, disability pension, welfare recipiency and low educational attainment.

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Does taking antidepressants during pregnancy harm the child? Here are the facts

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Ian Jones summarises a number of studies that consider the benefits and harms of antidepressants during pregnancy, including a recent cohort study that found that exposure to antidepressants in the womb is associated with a modest increased risk of speech and language disorders.

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Bipolar disorder in older men linked to increased risk of dementia

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Elena Marcus presents a recent study that shows how older Australian men with bipolar disorder have an increased risk of dementia and early death.

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Depression and coronary heart disease: reasons to remain UPBEAT-UK

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Kirsten Lawson summarises the UPBEAT-UK programme of research into the relationship between coronary heart disease and depression and anxiety in primary care patients.

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Lithium for bipolar disorder: the best maintenance mood stabiliser protection against self-harm and suicide?

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Michael Ostacher provides a robust appraisal of a recent UK cohort study that suggests bipolar disorder patients taking lithium had reduced self-harm and unintentional injury rates, when compared with patients taking valproate, olanzapine or quetiapine.

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Alcohol use disorder and increased mortality

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Matt Field summarises a recent Swedish longitudinal cohort study of alcohol use disorder and mortality across the lifespan. This study quantifies the environmental and genetic risk factors that contribute to increased mortality in people with alcohol use disorder.

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Self-harm on the rise, but many denied mental health assessments

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Katrina Witt explores a recently published paper that draws on the Multicentre Study of Self-Harm in England. The cohort study found that around one-half of self-harm patients do not receive psychosocial assessment, despite 2004 NICE guidance that recommends everyone who has self-harmed should have a comprehensive assessment of needs and risk.

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