51 studies were included in this Cochrane review of chlorhexidine mouthwash as an adjunct to mechanical oral hygiene measures. The review provides high quality evidence for a large reduction in the build-up of plaque at 4 to 6 weeks or 6 months. There is also high quality evidence of a moderate reduction in gingivitis in patients with mild gingivitis which may not be clinically important.
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Ioana Cristea summarises the latest Cochrane review on CBT, third-wave CBT and IPT based interventions for preventing depression in children and adolescents
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Joanne Wallace summarises the recent Cochrane systematic review on risperidone versus placebo for schizophrenia, which concludes that the best available evidence does not show that the benefits of risperidone outweigh the harms.
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14 trials were included in this Cochrane review of non-pharmacological interventions for orthodontic pain. The findings were inconclusive although there is some evidence that low-level laser therapy may help.
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The Cochrane review of of materials for retrograde root filling identified 6 RCTs all at high risk of bias. The trials provide insufficient evidence to draw any conclusion as to the benefits of any one material over another so more high quality studies are needed.
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This Cochrane review update included 25 RCTs comparing single verses multiple root canal treatment approaches. They found no evidence to suggest that one treatment regimen is better than the other.
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This update of a 2005 Cochrane review identified 23 RCTs but a limited number at low risk of bias so there is insufficient evidence to support or refute the use of any interventions in managing burning mouth syndrome.
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This Cochrane review of liners under posterior composite restoration included 8 RCTs identifying little evidence to show that they reduced sensitivity and no evidence of an effect on longevity of restorations.
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38 RCTs were included in this Cochrane review update of oral health care in ventilated patients. High quality evidence was found to show that chlorhexidine mouthwash or gel reduces the risk of developing ventilator-associated pneumonia in critically ill patients from 25% to about 19%.
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20 RCTs are included in this Cochrane review update of endodontic retreatment. The available evidence is of low quality so further research is needed to understand the effects of surgical versus non-surgical approaches, and to determine which surgical procedures provide the best results.
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