Vicky Carlisle publishes her debut elf blog on a Cochrane review of supervised dosing with long-acting opioid medication in the management of opioid dependence.
[read the full story...]
Only 9 small RCTs were included in this Cochrane review of metal-free materials for prosthodontic restorations providing insufficient evidence to support or refute the effectiveness of metal-free materials for fixed prosthodontic treatment over metal-ceramic or other type of standard restorations.
[read the full story...]
This Cochrane review of cytokines and growth factors for preventing oral mucositis in patients having cancer treatment included 35 RCTs finding keratinocyte growth factor beneficial in the prevention of oral mucositis .
[read the full story...]
Elena Marcus presents the findings of an updated Cochrane review on antipsychotic combinations for schizophrenia.
[read the full story...]
This Cochrane review of fluoride supplements during pregnancy for the prevention of caries in their children identified only a single trial which provided no evidence of caries prevention in their offspring.
[read the full story...]
This Cochrane review of orthodontic treatment for class II div 2 malocclusion updates the previous 2006 version. No RCTs or CCTs were identified so It is not possible to provide any evidence-based guidance to recommend or discourage any type of orthodontic treatment to correct Class II division 2 malocclusion in children.
[read the full story...]
This Cochrane review of drugs for the prevention of radiation-induced salivary gland dysfunction included 39 studies, while a range of agents was tested the evidence found is not sufficient to highlight much promise in terms of effective preventative treatments.
[read the full story...]
38 trials were included in this updated Cochrane review of the effect of fissure sealants on occlusal caries. The data show a reduction in caries of between 11-51% at 24months compared to no sealant. The benefit was also maintained at longer-term follow up.
[read the full story...]
15 RCTs were included in this Cochrane review of impact of periodontal treatment on adverse pregnancy outcomes. all the included studies were considered to be at high risk of bias. There was no evidence that periodontal treatment reduces the number of preterm babies.
[read the full story...]
This large, well-conducted study in a primary care setting found a small, but not statistically significant difference, between fissure sealants and fluoride varnish for the prevention of caries in first permanent molars at 36 months.
[read the full story...]
