We don’t know how to improve medicine adherence, says new Cochrane review

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Helge Hasselmann reports on a new Cochrane systematic review of interventions for enhancing medication adherence, which finds insufficient evidence to draw any conclusions. The full health benefits of medicines will not be realised until better interventions and better studies are conducted in this area.

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Psychotherapy for medically unexplained physical symptoms

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Ioana Cristea reviews a recent Cochrane systematic review on non-pharmacological interventions for medically unexplained physical symptoms (MUPS). The review finds that psychotherapies for MUPS led to reduced symptom severity, but were associated with a higher drop-out rate than usual care.

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Oral hygiene: professional cleaning and motivation helped during orthodontic treatment

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Eight RCTs were summarised in this review suggesting that regular patient motivation sessions and cleaning by a hygienist helped maintain good oral hygiene. No quantitative summaries was conducted so the magnitude of the benefit is unclear.

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Manual therapy and exercise for adhesive capsulitis

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This systematic review examines the effectiveness of manual therapy and exercise on adhesive capsulitis (frozen shoulder) a common cause of shoulder pain and stiffness.

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Local anaesthetic to reduce pain of dental care under general anaesthesia – evidence unclear

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This Cochrane review included 14 trials of variable quality that could not be combined due to variation in local anaesthetic delivery and outcome measures. So the results from individual studies for pain, bleeding and other adverse effects are uncertain.

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Slow-release fluoride devices: review finds insufficient evidence to show they reduce dental decay

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This new update of a Cochrane review only identified 1 study that randomised 174 children but analysed only 63. While there was a reduction in caries in those children with the slow-release fluoride glass bead the study is at high risk of bias and provides insufficient evidence to determine the caries-inhibiting effect of slow-release fluoride glass beads.

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Zinc supplements may have some benefit in treating taste disorders

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Taste disorders can have a impact of health and quality of life. This new Cochrane review identified 9 trials (566 participants) and found some evidence that zinc supplements could improve taste perception in people with idiopathic taste disorders. However the evidence is not of high quality.

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Short-term psychodynamic psychotherapy for all common mental health disorders?

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For his ninth Mental Elf blog, Mark Smith reports on a Cochrane systematic review of the effectiveness of short term psychodynamic therapies on common mental health disorders.

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Cultural competence education for health professionals: does learning about culture make any difference to patients?

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John Baker summarises a recent Cochrane systematic review of cultural competence education for health professionals, which tentatively concludes that low quality evidence supports this approach.

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