Kirsten Lawson reports on a recent Cochrane systematic review, which highlights a lack of high quality trials about the efficacy and safety of antidepressants for depression in cancer.
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In this blog, Tracey Howe looks at a Cochrane systematic review, examining the effects of exercise therapy for patients with Chronic Fatigue Syndrome.
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Dochka Hristova reports on a new Cochrane review of pharmacological interventions for self-harm in adults, which looks at the treatment effect on repetition of self-harm of antidepressants, antipsychotics, mood stabilisers and dietary supplements.
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This trial compared eugenol dressing or chlorhexidine gel for dry socket prevention against no intervention. Both agents reduced the incidence of dry socket but the reduction was greater with eugenol.
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Andrew Shepherd summarises a Cochrane systematic review of treatments for delusional disorder, which finds only 1 small RCT looking at treating the condition with medication or psychotherapy compared to placebo.
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This Cochrane review only identified 4 small short-term trials providing limited evidence for the effectiveness of surgical approaches to accelerate orthodontic treatment. Further research with longer follow up is needed to confirm any possible benefit.
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The review of sleep bruxism was only able to identify 12 small low quality RCTs covering a range of treatments. Most evidence was available for oral appliances but there is no sufficient evidence to state that the occlusal splint is effective for treating sleep bruxism.
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This Cochrane review identified 155 studies with 107 contributing to the quantitative analysis. There was a 35% reduction in dmft and a 26% reduction in DMFT. There was an approximately 15% increase in the percentage of caries-free children after water fluoridation. At a fluoride level of 0.7 ppm, the percentage of participants with fluorosis of aesthetic concern was approximately 12%.
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This review focused on lingual orthodontic retention including 27 studies (9 RCTs; 6 prospective and 12 retrospective studies). However, the quality of evidence was low, providing little evidence for the best treatment protocols.
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The update of the 2002 Cochrane review of fluoride included 28 trials finding an average 28% reduction (95% CI; 19-36%) in decayed, missing and filled tooth surfaces. There is little information about adverse effects or how well children and young people were able to cope with the gel application.
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