Institutional smoking bans reduce secondhand smoke exposure and harms, but more research is needed

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Olivia Maynard summarises a recent Cochrane systematic review about the impact of institutional smoking bans on reducing harms and secondhand smoke exposure in hospitals, universities and prisons.

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Prolonged bleeding after tooth extraction – no evidence on treatment from trials

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This Cochrane review did not identify any randomised controlled trials that evaluated the effects of different interventions for the treatment of post-extraction bleeding. Clinicians must use their clinical experience to determine the most appropriate means of treating this condition, depending on patient-related factors.

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Cochrane find no evidence for as required PRN medication for mental health inpatients

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John Baker summarises an updated Cochrane review on ‘as required’ PRN medication regimens for seriously mentally ill people in hospital, which finds no randomised controlled trials that support this widely used intervention.

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Psychosocial interventions for cannabis use disorder #CannabisMatters

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Ian Hamilton presents the findings of a recent Cochrane review, which finds that despite the large number of cannabis users seeking treatment, we still know relatively little about the best psychosocial interventions for cannabis use disorder.

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Treatment for depression in traumatic brain injury: Cochrane find no evidence for non-pharmacological interventions

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Eleanor Kennedy summarises a recent Cochrane systematic review, which finds no evidence to support the use of non-pharmacological interventions for depression in traumatic brain injury.

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Oro-antral communications – insufficient evidence for treatment approaches

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This Cochrane review of interventions for hte management of or-antral communications only identified 1 small trial which provides insufficient evidence for management of oro-antral communications.

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Infraorbital nerve block for postoperative pain following cleft lip repair in children

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This Cochrane review of Infraorbital nerve block for postoperative pain after cleft lip repair includes 8 trials providing low to very low quality evidence that infraorbital nerve block with lignocaine or bupivacaine may reduce postoperative pain more than placebo

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Crisis intervention for severe mental illness: Cochrane call for more evidence

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John Baker is struck by the lack of evidence for crisis intervention for people with severe mental illness, highlighted by a recently updated Cochrane systematic review.

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Adhesively bonded amalgams – insufficient evidence of better performance

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This Cochrane review update only identified 1 RCT assessing the difference in survival between bonded and non-bonded amalgam restorations providing insufficient evidence to support or refute a difference.

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Methylphenidate for ADHD: have Cochrane got it wrong this time?

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Chris Hollis appraises a recent Cochrane systematic review, which casts doubt over the quality of trial evidence and the clinical effectiveness of Methylphenidate for ADHD.

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