This review comparing the periodontal status of normal children with those living with diabetes regardless of type included 11 studies. While the findings suggest that children and adolescents with diabetes have poorer periodontal status the quality of the evidence is low.
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This review of the efficacy of adjunctive subgingival administration of chlorhexidine gel in nonsurgical periodontal treatment for chronic periodontitis included 17 RCTs only one of which was at low risk of bias for all domains. Findings suggest an improvement in pocket probing depth but not for clinical attachment.
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This review of the association between cannabis use and periodontal disease includes 5 observational studies and suggests a positive relationship.
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This review of the impact of fixed appliance orthodontic treatment on clinical attachment levels included 9 small prospective studies finding no no clinically relevant detrimental effect. However the overall level of evidence is low to very low.
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12 observational studies were included in this review of the effect of khat chewing on periodontal tissues. The available evidence is of limited quality but it suggests that khat use has an adverse effect on periodontal status.
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This review looked at the impact of gingival retraction on periodontal health. Only 10 small studies were available so which no method seems significantly superior the quality of the available evidence is limited.
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4 small RCTs of probiotics as an adjunct to scaling and root planing for management of chronic periodontitis were identified for this review. While a statistical significant benefit was demonstrated the limited number of small studies means that these findings should be interpreted with caution.
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This review of salivary biomarkers for diagnosing periodontal disease only identified 4 studies at high risk of bias but suggests a small number of potential biomarkers. However the findings should be interpreted with caution.
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This review of systemic antibiotics and non-surgical periodontal therapy for aggressive periodontitis included 13 RCTs and suggests a statistically significant benefit compared to non-surgical therapy alone.
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13 small RCTs were identified for this review, comparing full mouth interventions with quadrant scaling for periodontitis. Limited evidence of a small benefit was found in two comparisons.
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