This review of different topical medications for the management of recurrent aphthous stomatitis (RAS) included 43 RCTs. No significant differences were found for any if the treatments assessed and a majority of the included RCTs (76%) were considered to be at high risk of bias.
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This review of the level of toothbrush contamination and the factors affecting contamination in the general population included 15 studies. The findings show that toothbrush contamination occurs after first use and rises with continuing use. However, there is little evidence of significant adverse events from current practices.
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This review of oil pulling compared to chlorhexidine and other mouthwashes in improving the plaque, gingival and bacteria count parameters included 25 RCTs. However, the studies are modest in size of short duration and all except one study were considered to be at high risk of bias. Consequently the available evidence is of very low certainty and should be interpreted cautiously.
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This review of the effectiveness of patient-performed or administered adjunctive measures to non-surgical peri-implantitis therapy included 9 RCTs. A wide range of interventions were tested but the studies were mainly small with only one being at low risk of bias. Consequently addition high quality well conducted studies are needed on both the prevention and treatment of peri-implant disease.
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This review of the effect of different mouthwashes on gingival healing used after oral surgery in adults included 13 RCTs. The trials assessed 12 different products and concentrations and only one RCTs was considered to be at low risk of bias so the findings should be interpreted cautiously.
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This review of the efficacy of chlorhexidine (CHX) products in maintaining gingival health in orthodontic patients with fixed appliances included 20 RCTs only 1 of which was at low risk of bias. The findings showed a benefcial effect on gingival parameters with CHX mouthwash at 1-3 months but the findings should be interpreted cautiously.
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This review of the efficacy of mouthwashes on oral microorganisms and gingivitis in orthodontic patients included 32 RCTs. While the findings suggest short-term benefits with adjunctive mouthwash use the findings should be intertpreted cautiously as only one RCT was at low risk of bias and for almost all outccomes the certainty of evidence was rated as very low to low.
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In this blog Thibault Collloc looks at a review of is the effectiveness of instrumentation and irrigation with NaOCl and EDTA compared to any other root canal irrigant. The review was one of a number undertaken to inform guidelines for the European Society of Endodontics.
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This review of the effectiveness of sodium bicarbonate in the prevention and management of oral mucositis included 11 RCTs. The included studies were small, hetrogeneous and suggested little benefit from the use of sodium bicoarbonate mouthwashes.
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This review of the efficacy and safety of topical interventions used for recurrent aphthous stomatitis included 72 studies assessing 29 different interventions. Most of the interventions did not demonstrate significant differences with limitednumbers of studies for some interventions and overal limitations in the quality of the evidence.
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