Cannabis use can lead to relapse in psychosis, partially because patients stop taking medication

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Thomas Richardson writes his debut blog about a recent prospective analysis of poor medication adherence and risk of relapse associated with continued cannabis use in patients with first-episode psychosis.

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Cannabis and psychosis: it’s high time for a review

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Joe Barnby considers the findings of a recent meta-analysis of cannabis use and symptoms severity in individuals at ultra-high risk for psychosis.

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Sex matters: why have females been excluded from addiction research?

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Ian Hamilton explores two recent articles that consider the shocking sex and gender inequities in addiction research.

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Cannabis: what do we know and what do we need to know?

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Ian Hamilton considers a recent literature review published in JAMA Psychiatry, which explores the effects of cannabis use on human behaviour, Including cognition, motivation and psychosis.

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Does tobacco use cause psychosis?

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Marcus Munafo appraises a recent systematic review and meta-analysis of prospective, case-control and cross-sectional studies, which finds that daily tobacco use is associated with an increased risk of psychosis and an earlier age at onset of psychotic illness.

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Alcohol use confounds the relationship between cannabis use and conversion to psychosis

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Kathryn Walsh presents a study of ‘high risk’ young people, which found that cannabis abuse or dependence significantly increased the risk of conversion to psychosis. The research also found that alcohol use weakened the relationship between cannabis use and conversion to psychosis.

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High potency cannabis and the risk of psychosis

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Eleanor Kennedy writes her debut blog on a recent case-control study of people in South London, which explores the links between first-episode psychosis and the use of high potency cannabis (skunk).

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Childhood abuse and adverse life events interact synergistically to produce a high risk for psychotic experiences

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This recent study concludes that childhood abuse creates an enduring vulnerability to psychosis that is realised in the event of exposure to further stressors and risk factors, such as separation, bereavement, or being involved in an accident or physical attack.

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Cannabis, cigarette smoking and psychosis: do we need a rethink?

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The relationship between cannabis and psychosis has been one of the hottest topics in psychiatry over the last decade, and with good reason. Policy-makers still disagree on whether cannabis should be legalised or how it should be classified, with Uruguay being the most recent country to legalise it. Drawing broadly from work initiated by Robin [read the full story…]

NICE publish new evidence summary on psychosis with coexisting substance misuse

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The NICE guideline on psychosis with coexisting substance misuse was published in 2011, which means it’s now nearly 3 years out of date. This is because guidelines take many months to produce, so by the time they are published the evidence in them is 1 year old at best. Some NICE guidelines are supplemented by [read the full story…]