This ‘optimal use’ project from the Canadian Agency for Drugs and Technologies in Health assesses the clinical and economic impact of using atypical antipsychotic combination therapy, as well as high-dosing treatment strategies, in adolescents and adults with schizophrenia. The report was produced by an expert panel who based their recommendations on a systematic review and [read the full story…]
This Canadian rapid response report will be of interest to anyone looking for a general introduction to the high level evidence relating to hospital admission and the treatment of patients with anorexia nervosa. The authors found 1 meta-analysis, 2 systematic reviews and 3 guidelines, but no health technology assessments. They summarised their findings as follows: [read the full story…]
Benzodiazepines are most commonly prescribed for the management of anxiety and insomnia. They can also be used for sedation or amnesia before medical or surgical procedures, treatment of seizure, treatment of alcohol or sedative withdrawal, or acute agitation. Known side effects include drowsiness, fatigue and ataxia (the loss of full control of bodily movements). Opioids [read the full story…]
Unsurprisingly, research shows that people who have deviant sexual preferences are more likely to commit sexual offences, so it makes sense that if we can more accurately identify deviant sexual preferences, we will be able to reduce crimes of this nature. Phallometry (also known as penile plethysmography or phallometric assessment) involves placing a device around [read the full story…]
Attention deficit hyperactivity disorder (ADHD) is a group of behavioural symptoms that include inattentiveness, hyperactivity and impulsiveness. ADHD is often thought of as a childhood problem, but it can be a lifelong condition, and many children continue to have symptoms as a teenager and adult. It is estimated that nearly two-thirds of children with ADHD [read the full story…]
This rapid response report from the Canadian Agency for Drugs and Technologies in Health set out to answer four questions: 1. What is the evidence on the safety of using benzodiazepines in older adults to manage disruptive behaviour or treat anxiety? 2. What is the effectiveness of benzodiazepines compared with that of antidepressants in older [read the full story…]
