New meta-analysis finds methadone better than buprenorphine for treatment retention in opioid dependence

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Ian Hamilton considers a new Lancet Psychiatry systematic review and meta-analysis that examines the effectiveness of buprenorphine versus methadone for the treatment of opioid dependence, drawing from observational and randomised controlled studies.

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A human rights approach to integrating HIV and substance misuse services

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Andie Ashdown and Theophanis Kyriacou summarise a recent paper on integrating HIV and substance misuse services, which draws on a person-centred approach that is grounded in human rights.

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Can a ‘personalised psychosocial toolbox’ help people reduce ‘on-top’ drug use during opioid substitution treatment?

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Vicky Carlisle summarises a promising recent RCT on the efficacy and cost-effectiveness of an adjunctive personalised psychosocial intervention in treatment-resistant maintenance opioid agonist therapy.

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Opiate substitution therapy: supervised-consumption vs take-home doses

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Vicky Carlisle publishes her debut elf blog on a Cochrane review of supervised dosing with long-acting opioid medication in the management of opioid dependence.

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How does buprenorphine fair as an alternative to methadone for treating opioid dependence?

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Meg Fluharty summarises a recent Cochrane review, which tells us that high-dose buprenorphine is an effective maintenance treatment for heroin compared to placebo, but fixed flexible-dosing methadone is superior to buprenorphine at participant retention.

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Interventions for drug using offenders: What works in reducing drug use and criminal activity?

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It is estimated that between 10% (Gunn 1991) and 39% (Brooke 1996) of prisoners in the UK are dependent on illicit drugs; and that 14.5% of male and 31% of female prisoners have serious mental health problems (Steadman 2009). Drug use can be associated with many health, social and criminological consequences; and when mental health [read the full story…]