This review assessing the effectiveness of topical interventions in the management of burning mouth syndrome (BMS), based on the core outcome domains recommended by the Initiative on Methods, Measurement, and Pain Assessment in Clinical Trials (IMMPACT) includes 8 RCTs and higlights the need to apply standardised outcome measures in future studies.
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This review of the risk of hyperaesthesia with articaine compared with other local anaesthetics in lower alveolar nerve block for lower third molar removal included 13 studies.The findings suggest that the use of articaine does not increase the risk of hyperaesthesia.
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This review of the effectiveness of different anaesthetic solutions for pain control immediately after the extraction of lower third molars included 45 studies.13 studies were included in a network meta-analys whch suggested 5% bupivacaine reduces pain in patients during and immediately after the removal of lower third molars.
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In this blog Manàs Dave looks at a systematic review of treatment options for patients with Burning Mouth Syndrome (BMS). Study heterogeneity means that only a narrative summary was possible so there is a need for high quality research in this area.
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This review comparing the efficacy and safety of currently available local anaesthetics for lower third molar extraction included 24 RCTs. The findings suggest that 4% articaine was the most effective and lidocaine the safest.
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This review of the most effective anaesthetic solutions for inferior alveolar nerve blocks for mandibular teeth with irreversible pulpitis included 11 RCTs. The findings suggest that mepivacaine with epinephrine performed better than lidocaine with epinephrine but the number of trials is limited and the quality of evidence was very low to moderate.
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123 RCTs were included in this Cochrane review of local anaesthetic agents for preventing pain during dental treatment. 14 types of local anaesthetic were included evidence to support the use of one over another was limited so further research is needed to clarify the effectiveness and safety of one local anaesthetic over another.
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This Cochrane review of Infraorbital nerve block for postoperative pain after cleft lip repair includes 8 trials providing low to very low quality evidence that infraorbital nerve block with lignocaine or bupivacaine may reduce postoperative pain more than placebo
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Elimination of pain during and after root canal treatment is an important element of patient care and modern endodontic practice. The aim of this study was to compare the postoperative pain and analgesic use after single-visit root canal treatment of acute irreversible pulpitis with either bupivacaine (a long-acting anaesthetic) or lidocaine. Patients with a first [read the full story…]
Local anaesthetic use is widespread in dentistry and while lidocaine has been in use for more than 50 years an increasing number of agents are now available. The aim of this study was to analyze adverse drug reactions (ADRs) associated with local anesthetics (LAs) and to characterize the safety profile of LAs in clinical application. [read the full story…]
