New and emerging treatments for major depressive disorder

Sprouts of hope for treatment resistant depression?

Kirsten Lawson summarises a new ‘state of the art review’ in the BMJ which focuses on novel and emerging pharmacotherapy and neuromodulation for people with ‘treatment resistant depression’.

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Light therapy may help reduce depression during pregnancy, says small randomised controlled trial

shutterstock_52133623 depression pregnancy

Depression commonly occurs during pregnancy and it’s often a challenging condition to treat as the health of the mother has to be balanced with the potential risks that can be caused to the foetus by antidepressant drugs. Pilot trials have previously shown that light therapy may be a safe and effective treatment in this population, [read the full story…]

Bright light treatment helps elderly people with non-seasonal depression

bright light treatment

Major depressive disorder is a prevalent and debilitating condition in elderly patients. It is accompanied by circadian rhythm disturbances associated with impaired functioning of the suprachiasmatic nucleus, the biological clock of the brain. Circadian rhythm disturbances are common in the elderly. Suprachiasmatic nucleus stimulation using bright light treatment may, therefore, improve mood, sleep, and hormonal [read the full story…]