Catherine Harmer summarises a recent network meta-analysis relating to her own Wellcome Trust funded research into antidepressants for young people with anxiety or depression.
[read the full story...]Blinding in randomised controlled trials of oral health interventions and effect size estimates
In this blog Mark-Steven Howe looks at a methodlogical review and meta-analysis. The review looked at the use of patient and assessor blinding is trials of oral health interventions and shows larger effect sizes when blinding was lacking.
[read the full story...]Magic mushrooms promising for treatment resistant depression
Our #EvidenceLive team of bloggers report on a recent feasibility study of psilocybin for the treatment of refractory depression.
[read the full story...]Does the placebo effect inflate the effectiveness of psychotherapy?
Sarah Knowles reviews a recent meta-analysis about the effects of blinding on the outcomes of psychotherapy and pharmacotherapy for adult depression.
[read the full story...]Group psychotherapies for schizophrenia
Tracey Roberts appraises a systematic review of group psychotherapies for schizophrenia, which includes group CBT, music therapy, art therapy and social skills training.
[read the full story...]The PACE Trial for chronic fatigue syndrome: choppy seas but a prosperous voyage
Simon Wessely responds to the huge amount of recent criticism that has surrounded the publication of a follow-up paper of the PACE trial into chronic fatigue syndrome. This extended blog presents the PACE trial and its main results, but also reminds us what makes a good RCT, as well as exploring how well PACE measures up.
[read the full story...]Small but potential benefits of cryotherapy following total knee replacement surgery
Osteoarthritis of the knee is a common condition and typically presents with painful and restricted function and sometimes varus (bow legs) and valgus (knock knees) deformity of the knee. Once the condition and pain worsens knee joint replacement surgery is a treatment option. Patients typically improve in terms of pain and function but there is [read the full story…]