Meta analysis reveals different structural brain abnormalities in depression and bipolar disorder

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It has long been documented that there are clinical differences between depression and bipolar disorder, but to date there has been no reliable study that shows differences in structural brain abnormalities in the two disorders. A research team from the Institute of Psychiatry in London have published a meta analysis that investigates structural brain changes in [read the full story…]

Maintenance treatments for bipolar disorder: reducing the risk of manic, mixed or depressive relapse

Prescribing of medication for ADHD symptoms in young people with ASD is currently based on low quality evidence with a high risk of bias.

Many people with bipolar disorder have a range of therapies available to them nowadays, including mood stabilisers (or anticonvulsants), antipsychotics and various psychosocial interventions (including CBT, psychoeducation and family therapy). A research team from the University of Barcelona have published a meta-analysis that investigates the efficacy of drug maintenance treatments for bipolar disorder. They searched from [read the full story…]

Young men with bipolar disorder are more likely to drop out from online psycho-education programmes

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Web-based education support for people with health problems is now widespread, but there is comparatively little research that explores the reasons why people do not complete online courses once they are enrolled. This paper presents data from a randomised controlled trial based in Australia, where 370 participants were randomly allocated to: An online bipolar education [read the full story…]

Lithium is a better treatment for bipolar disorder than valproate

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Valproate is widely used as a mood stabiliser for people with bipolar disorder, despite the fact that there is very little evidence that shows the effectiveness of this treatment. This observational cohort study looked at over 4,000 bipolar patients in Denmark who were treated with lithium or valproate from 1995 to 2006. The results favoured [read the full story…]