People with serious mental health issues such as schizophrenia have higher rates of cigarette smoking than the general population, with estimates suggesting more than 50% are current smokers. When people in this population do manage to quit during treatment we then see particularly high rates of relapse after treatment ends. A new randomised control trial (Evins [read the full story…]
Bipolar disorder is an affective disorder marked by cycles between mania and depression. It has an early onset, with mean age ranging from 19 to 29 (Offord, 2012) and a prevalence of 0.5% – 4.3% in primary care alone, stretching to 9.3% in some settings (Cerimele, Chwastiak, Dodson, & Katon, 2013). With its problematic recurring [read the full story…]
It has long been established that psychiatric disorders have a genetic component. In the early days of genetic research, twin and family studies were used to estimate heritability (the proportion of variance explained by genetic factors). The Psychiatric Genetics Consortium has recently published a paper in Nature Genetics to assess the heritability and co-inheritability (relationship between [read the full story…]
A cohort study published in JAMA tried to answer the question what are the risk factors for suicide in the US military. This is a hot topic as the rate of suicide has increased in US military personnel from about 11/100,000 people in 2005 to about 18/100,000 so that now deaths from suicide outnumber deaths [read the full story…]
Individuals with severe mental illness (SMI) have shortened life expectancies compared to the general population. This is partly down to higher rates of chronic physical illness. Cardiovascular disease (CVD) is the leading cause of death among patients using mental health services. It is assumed that interventions used to reduce CVD are similarly effective in patients with [read the full story…]
People with bipolar disorder are found to be at greater risk of suicide compared to the general population. Clinicians should be more vigilant for signs of suicidality in this patient group. Suicide, the taking of one’s own life, sadly is the cause of death for around 5,500 people in the United Kingdom each year. In [read the full story…]
NICE has just published a new technology appraisal recommending aripiprazole as a treatment for bipolar disorder in young people. Technology Appraisals are systematic evaluations of the effectiveness of health technologies. They do not have the broad scope of guidelines, which focus on topics rather than technologies, but they do give guidance for clinical practice on the [read the full story…]
Bipolar disorder is considered a hereditary condition. There is emerging evidence that prodromes/early symptoms are evident in children before disorders develop. This potentially offers a chance to treat and prevent the development of mental health problems in adulthood. Being able to identifying early symptoms of the onset of this mental health disorder is clearly important, however, [read the full story…]
People with serious mental illness have mortality rates 2-3 times as high as the general population. The primary cause of death is cardiovascular disease, which in turn is due to an extremely high prevalence of obesity (twice that of the overall population). Physical inactivity, unhealthy diets, and weight gain from psychotropic medication are all factors [read the full story…]
When trying to understand more about about mental health problems one of the big questions is: are the results of a study due to how the person is currently feeling or are the results due to a predisposition to how they are feeling now? While often the answer will be a bit of both, researchers [read the full story…]
