Mood Matters: mood instability is common and associated with poor outcomes

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Farhana Mann summarises an observational study of mood instability in people with mental illness, which explores its relationship with days spent in hospital, frequency of admissions, the likelihood of being sectioned and the chance of being prescribed antipsychotics and mood stabilisers.

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Smoking cessation for people with severe mental illness

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Sally Adams appraises and summarises the SCIMITAR pilot RCT, which investigates smoking cessation for people with severe mental ill health. The paper presents a highly promising bespoke intervention for smokers with bipolar disorder, psychosis or schizophrenia.

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Premature mortality in bipolar disorder

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Elena Marcus appraises a recent systematic review and meta-analysis of premature mortality in bipolar affective disorder, which finds that people with bipolar disorder have increased mortality rates compared with the general population.

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Screening for bipolar spectrum disorders (MDQ, BSDS and HCL-32)

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Elena Marcus appraises a recent meta-analysis of screening for bipolar spectrum disorders, which concludes that the MDQ and HCL-32 tools are supported by more evidence than the BSDS tool.

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The antidepressant effects of ketamine are confirmed by a new systematic review and meta-analysis

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Helge Hasselmann summarises a new systematic review and meta-analysis, which confirms the antidepressant effects of ketamine.

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People with severe mental illness are more likely to be victims of violent and non-violent crime

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Vishal Bhavsar summarises a recent cross-sectional study of violent and non-violent crime against adults with severe mental illness, which finds that service users were five times more likely to be victims of assault, and three times more likely to be victims of household acquisitive crime.

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Searching for the cost of bipolar disorder

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Bipolar disorder is associated with high economic costs…or is it? Chris Sampson reports on a new systematic review, which highlights limitations in our understanding.

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Compulsory community treatment results in no significant difference in service use, social functioning or quality of life

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Rebecca Syed appraises and summarises an updated Cochrane review of compulsory community treatment and involuntary outpatient treatment for people with severe mental disorders. The review finds just 3 trials, which show that CCT results in no significant difference in service use, social functioning or quality of life.

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Psychotherapies for anxiety in bipolar disorder

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Elena Marcus finds inconclusive results in this recent systematic review of psychological therapy for anxiety in bipolar spectrum disorders, which includes trials of CBT, mindfulness based cognitive therapy and stress management therapy.

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Prescribing antipsychotics in primary care: new study highlights frequent off-label use

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Josephine Neale reports on a recent cohort study that finds less than half of UK prescriptions for antipsychotics are issued for main licensed conditions (e.g. psychosis or bipolar disorder). The research provides a reminder about the dangers of prescribing antipsychotics to people with dementia.

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