Crisis intervention for severe mental illness: Cochrane call for more evidence

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John Baker is struck by the lack of evidence for crisis intervention for people with severe mental illness, highlighted by a recently updated Cochrane systematic review.

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Is the NICE guideline for bipolar disorder biased in favour of psychosocial interventions?

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Guy Goodwin reviews a new paper in the Lancet Psychiatry by Jauhar, McKenna and Laws, that calls into question the trustworthiness of the NICE bipolar disorder guidance.

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Lamotrigine, quetiapine and folic acid for bipolar depression: the CEQUEL trial

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Michael Ostacher considers the findings of the CEQUEL trial, which asks: Does lamotrigine treat bipolar depression when added to quetiapine, and does adding folic acid help any more?

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Does QOF reduce hospitalisation for people with severe mental illness?

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Andres Fonseca appraises a regression analysis looking at the quality and outcomes framework (QOF) and the impact it has on psychiatric admissions in people with severe mental illness.

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Smoking and chronic mental illness: what’s the best way to quit or cut down?

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Meg Fluharty considers the findings of a BMJ State of the Art review, which looks at the evidence for smoking cessation in people with chronic mental illness such as schizophrenia, unipolar depression, bipolar depression, anxiety disorders and PTSD.

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Improving diagnosis of bipolar disorder: can blood-based diagnostic panels help?

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Can blood-based diagnostic panels help us reduce the misdiagnosis and inappropriate treatment often experienced by people with bipolar disorder? Murtada Alsaif reviews a recent retrospective study that has some encouraging findings for biologically identifying the disease.

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Early intervention in psychosis: how long is long enough?

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Rachel Brand looks at a recent RCT which investigates the optimal duration of an early intervention in psychosis programme for young people in Hong Kong.

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Lifetime prevalence of anxiety disorders in people with bipolar disorder

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Alan Underwood appraises a recent meta-analysis that finds anxiety disorders are three times more common in people with a diagnosis of bipolar disorder.

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What impact are psychotropic drugs having on our physical health?

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John Baker summarises the findings of a recent review of people with schizophrenia, bipolar disorder and depression. The study looks at the adverse effects on physical health of psychotropic drugs (antipsychotics, antidepressants and mood stabilisers).

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