Dual antiplatelet therapy and post-operative bleeding following minor oral surgery

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This review of bleeding complications in patients on dual antiplatelet therapy compared to patients on single antiplatelet or no antiplatelet therapy for patients undergoing oral surgery included 16 studies but no randomised trials. Findings suggest that dual antiplatelet therapy should not be discontinued but the evidence is of low quality.

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Wealth of reliable evidence on efficacy of single dose oral analgesics

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This overview includes 39 Cochrane reviews with data from around 460 studies and about 50,000 patients providing a wealth of reliable evidence on the analgesic efficacy of single dose oral analgesics.

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Few adverse events with single dose oral analgesics for acute postoperative pain

This overview of adverse event rates associated with single dose oral analgesics includes data from 39 Cochrane reviews, and provides evidence that adverse events rates are generally similar with active drug and placebo.

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Tooth extraction: no need to stop long-term aspirin before suggests review

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This review considers whether patients on long-term aspirin therapy should stop aspirin before tooth extraction. The review found 10 studies (3 RCTs). No significant increase in bleeding time was found and although there was an increased risk of haemorrhage, the authors recommended not stopping aspirin therapy.

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