This review and network meta-analyses of the effectiveness of self-applied dentifrices in the management of dentine hypersensitivity included 68 studies. Findings indicated that formulations including stannous, potassium +/- stannous, and arginine result in significant short ( 2-weeks) and long term inprovements. However the studies were hetrogeneous and only 4 were at low risk of bias.
[read the full story...]
This review of treatments used to treat dentine hypersensitivity. 254 different agents were tested with all showing some effectiveness in short term.
[read the full story...]
This network meta-analysis comparing the effect of different desensitising toothpastes on dentine hypersensitivity included 30 RCTs. The findings suggest that toothpastes containing nano-hydroxyapatite or arginine may be the most effective. However additional larger studies are required.
[read the full story...]
This review evaluating the effectiveness of desensitising toothpastes included 53 RCTs. Most agents with the exception of those containing strontium or amorphous calcium phosphate were effective in relieving dentine hypersensitivity compared with negative controls.
[read the full story...]
7 RCTs were included in this review of the caries prevention effects of arginine containing dental products. They provide insufficient evidence to support a caries preventive effect for arginine in toothpaste.
[read the full story...]
Ten trials were included in this review of arginine in toothpaste. It found that arginine in combination with calcium bases (either Dical or calcium carbonate) and fluoride provided a superior effect compared with fluoride alone. However, 9 out of 10 of the trials were sponsored by a single company and the overall quality of the evidence was considered to be low.
[read the full story...]
This review of dentine hypersensitivity treatment was broad, covering 11 agents and 105 RCTs. Most treatments suggested some benefits but the quality of available evidence was limited and there was little information on the relative effectiveness of the various agents.
[read the full story...]
In this small trial the use of either an 8% arginine desensitising paste or prophy paste reduced dentine hypersensitivity after scaling but the arginine base paste was significantly better than the standard prophy paste.
[read the full story...]
31 RCTs were identified for this review of desensitising toothpastes for dentine hypersensitivity. A wide range of agents were tested and most were found to be effective although the number of trials available for each agent was relatively small range from 3-8 studies.
[read the full story...]
Cochrane reviews have clearly documented the anti-caries benefits of fluoridated toothpastes (Marhino et al 2003, Walsh et al 2010). New agents to improve caries prevention would assist efforts to reduce the impact of caries, particularly on children. The aim of this study was to investigate the efficacy of two dentifrices containing 1.5% arginine, an insoluble [read the full story…]
