This review of the the effectiveness of different mandibular advancement devices for obstructive sleep apnoea included 50 RCTS. While the findins suggest that mono-bloc MADs are more effective duo-bloc devices the quality of the available evidence is very low.
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This Cochrane review to assess the effects of oral appliances or functional orthopaedic appliances for obstructive sleep apnoea in children only identified a single small trial which provided insufficient evidence to assess effectiveness.
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This review of the use of oral appliances for the treatment of obstructive sleep apnoea identified 17 trials, all but one of which wере randomised. The results suggest significant benefits in respiration and sleep quality, compared to placebo devices or blank control.
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Obstructive sleep apnoea-hypopnoea (OSAH) affects 2-7% of adults. This trial compared 3 mandibular advancement devices with no treatment for mild disease and found benefits over the short term for a range of outcomes including Apnoea-Hypopnoea Index, the Epworth Sleepiness Scale and cost-effectiveness.
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