Risk factors for depression relapse while on long-term maintenance antidepressant treatment

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In her debut blog, Asha Ladwa discusses a secondary analysis of data from the ANTLER trial, which investigated the clinical factors associated with relapse in primary care patients on long-term maintenance antidepressants.

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Maintenance or discontinuation of antidepressants for depression? Findings from the ANTLER trial

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For every 6 people stopping their medication there was one additional relapse compared to those who maintained their antidepressant treatment, suggesting that stopping medication has an increased risk of relapse.

Raphael Rifkin-Zybutz and Sameer Jauhar summarise the recently published ANTLER trial, which explores whether antidepressant maintenance can reduce the risk of relapse in depression.

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