Caroline Struthers scrutinises a systematic review on the longitudinal course of behavioural and psychological symptoms of dementia.
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Samei Huda mulls over a recent RCT on the effects of older and newer antipsychotics on quality of life in schizophrenia. The study finds a different result to the 10-year old CUTLASS trial; namely that second generation antipsychotics may be superior to first generation antipsychotics in terms of improving quality of life for people with schizophrenia.
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Alex Langford explores the emerging findings from a recent meta-analysis looking at the efficacy and safety of antidepressants added to antipsychotics for people with schizophrenia and schizophrenia-like psychosis.
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Murtada Alsaif summarises a recent 4-week long phase II randomised controlled trial of ITI-007 for the treatment of schizophrenia, which contains some positive results for this novel intervention.
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Joseph Hayes summarises the recent British Association for Psychopharmacology guidelines for the treatment of bipolar disorder, and compares their recommendations with those found in the NICE bipolar disorder guidance from 2014.
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Angela Hassiotis and James Dove summarise a recent meta-analysis of antipsychotic prescribing and use trends in US youth with autism spectrum disorder and/or learning disabilities.
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Andres Fonseca struggles to use the findings of a recent systematic review and meta-analysis of antipsychotics for the prevention and treatment of delirium in hospitalised adults.
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Tayla McCloud from the #UCLJournalClub presents the findings of a cohort study showing that antipsychotics are being over-prescribed in people with learning disabilities.
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John Baker summarises an updated Cochrane review on ‘as required’ PRN medication regimens for seriously mentally ill people in hospital, which finds no randomised controlled trials that support this widely used intervention.
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Tracey Roberts summarises a recent RCT of the efficacy and safety of paliperidone palmitate 3-month formulation for patients with schizophrenia.
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