Studies have suggested that anti-psychotic medications comprise between 30–50% of all psychotropics prescribed for people with learning disabilities, often prescribed for people with challenging behaviours with no diagnosis of mental illness. Reviews of their use have suggested however that there is no strong evidence supporting the anti-aggressive properties of anti-psychotics. This study in Australia was [read the full story…]
Non-pharmacological interventions can help prevent and reduce weight gain in people who take antipsychotics
The reduced life expectancy (15-20 years less) often faced by many people with schizophrenia is frequently a result of cardiovascular disease. Lifestyle choices (smoking, lack of exercise and poor diet) can increase the risk of these diseases, but people who take antipsychotic drugs often have the additional problem of weight gain that is caused by [read the full story…]
Cochrane review suggests adding promethazine to haloperidol to rapidly tranquillise psychotic patients with fewer side effects
The hallucinations and delusions associated with psychosis can be frightening and may sometimes result in aggressive or violent behaviour. Of course, this can be incredibly challenging for the patient, but it can also be a real test for mental health staff who have to try and minimise the harm that patients do to themselves and others. Haloperidol [read the full story…]
NICE publish evidence update on generalised anxiety disorder in adults
NHS Evidence have published an evidence update on generalised anxiety disorder in adults. Evidence updates are summaries of selected high quality evidence that has appeared since the relevant guideline was published, in this case NICE clinical guideline 113 ‘Generalised anxiety disorder and panic disorder (with or without agoraphobia) in adults: management in primary, secondary and community care’ [read the full story…]
Scotland sees increase in prescribing rates for mental health drugs
The Scottish Government have published their annual summary of prescribing statistics for mental health drugs. The report shows increases in the prescribing rates for all groups of drugs over the last 12 months. The prescribing costs of some groups of drugs have also risen (ADHD, dementia, depression) although other groups have seen a decline (insomnia [read the full story…]
Short-term use of second-generation antipsychotics can cause side effects in children and adolescents
Over the last few years, we have seen more and more children and young people being prescribed antipsychotic drugs. The theory behind this increase is that the newer antipsychotic drugs have fewer side effects than the older typical antipsychotics. However, some small and relatively short duration studies have shown that the newer drugs may also [read the full story…]
Psychosis and schizophrenia in children and young people: NICE starts consultation
The two month consultation period for the new NICE guideline on psychosis and schizophrenia in children and young people has now begun. You must be registered as a stakeholder to comment on the guideline and you have until 27th September 2012 to make your views known. The guideline is aimed at clinicians and service commissioners [read the full story…]
The risks of benzodiazepines, antidepressants and antipsychotics in adults with schizophrenia
Polypharmacy is the simultaneous use of two or more drugs to treat a single health condition. Polypharmacy is often used in the treatment of schizophrenia where people are regularly prescribed two or more antipsychotics, as well as antidepressants and/or benzodiazepines, although there is little evidence to prove that these combinations are more effective than monotherapy. [read the full story…]
Losing weight on antipsychotics. New systematic review looks at diet and exercise
Weight gain is one of the side effects that people who take antipsychotic drugs complain of the most. Obesity is common in this population and this can often lead to cardiovascular problems and a far shorter life expectancy than the rest of the population. As a result, there is a great deal of interest in [read the full story…]
Haloperidol reduces mania a little faster than second-generation antipsychotics, according to systematic review
There are a range of treatment options for people with bipolar disorder who are experiencing a manic episode. An important part of this treatment is to reduce the symptoms of mania and provide the individual with some level of normality. I blogged this time last year about a meta-analysis in the Lancet that showed that [read the full story…]