Nuala Murray explores a recent Australian case-control study that looks at the associations between changes in gut microbiota and schizophrenia diagnosis, treatment resistance, and clozapine response.
[read the full story...]Psychotropic medication during pregnancy: new umbrella review finds no convincing evidence of adverse health outcomes for the baby
Flo Martin summarises a recent umbrella review which finds that we still have limited knowledge about the safety of psychotropic drug use in pregnancy.
[read the full story...]Cognition and heterogeneity in first-episode psychosis before antipsychotic treatment
Ana Veic looks at an updated systematic review which suggests that patients with psychosis display cognitive difficulties very early in the disease process, and concludes this variation in cognitive function should prompt individual clinical assessments to optimise care.
[read the full story...]Antipsychotics and risk of violence and suicide in people diagnosed with personality disorders
A group of MSc students from UCL summarise a study examining the links between antipsychotics, risk of violent crimes and suicidal behaviour in people diagnosed with a ‘personality disorder’.
[read the full story...]Predicting treatment-resistant psychosis using routine clinical measures
Lorna Staines summarises a recent study on predicting treatment-resistant psychosis, which suggests that future risk prediction efforts should seek to consider routinely collected data.
[read the full story...]Optimal antipsychotic dosing in first-episode schizophrenia: how much is too little, too much, or just right?
Joe Pierre reports on the first published study exploring the relationship between antipsychotic dose and risk of relapse in first episode schizophrenia, which suggests that standard antipsychotic dosing is best for relapse prevention.
[read the full story...]Uncertainties about stopping or reducing antipsychotics as shared by families
Amelia Talbot considers a qualitative study that explores family members’ perspectives on reducing or discontinuing antipsychotic medication.
[read the full story...]Do different groups of people with schizophrenia respond differently to different antipsychotics?
Murtada Alsaif considers a systematic review and meta-analysis published in the Lancet Psychiatry exploring the response of different subgroups of patients with schizophrenia to different antipsychotic drugs.
[read the full story...]To stay on antipsychotics or not to stay on antipsychotics? A longstanding question with an update
Joe Pierre considers a recent network meta-analysis on continuing, reducing, switching, or stopping antipsychotics in individuals with schizophrenia-spectrum disorders who are clinically stable.
[read the full story...]Youth mental health interventions: umbrella review presents efficacy and acceptability data
In his debut blog, Nick Meader tackles a huge umbrella review of youth mental health interventions, which presents the efficacy and acceptability of 72 different approaches to help children and young people.
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