Peri-implantitis – adjunctive measures to non-surgical peri-implant therapy

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This review of the effectiveness of patient-performed or administered adjunctive measures to non-surgical peri-implantitis therapy included 9 RCTs. A wide range of interventions were tested but the studies were mainly small with only one being at low risk of bias. Consequently addition high quality well conducted studies are needed on both the prevention and treatment of peri-implant disease.

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Local and systemically delivered antimicrobials and surgical treatment of peri-implantitis

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This review of adjunctive systemic or local antimicrobials as an adjunct to surgical treatment of peri-implantitis included 4 RCTs. The included studies only included a total of 200 pateints and were all considered to be at high risk of bias. The studies antimicrobial and treatment protocols also showed marked variation. Consequently, there is little evidence available on the effectiveness of local or systemic antimicrobials as adjuncts to surgical treatment of peri-implantitis

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Clarithromycin as an adjunct to non-surgical periodontal treatment

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This review of systemic or locally delivered clarithromycin as an adjunct to non-surgical periodontal therapy included 7 small RCTs, 4 RCTS related to systemic use and 3RCTS for local application. The findings provide moderate certainty evidence suggesting locally delivered clarithromycin significantly improves treatment outcome

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Root canal disinfection: Sodium hypochlorite or chlorhexidine?

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This review comparing the antimicrobial efficacy of chlorhexidine (CHX) and sodium hypochlorite (NaOCl) in root canal disinfection included 8 small RCTs. While teh findings suggest that CHX and NaOCL have similar efficacy the certainty of teh availabel evidence is low.

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Scaling and root planing adjuncts for chronic periodontitis

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In 2015 the American Dental Association published a Guideline on nonsurgical treatment of chronic periodontitis. This network meta-analysis re-analyses the included studies providing a complementary appraisal of the data.

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Weak evidence suggests small additional benefit from the use of local antimicrobials as adjunct to scaling and root planning for chronic periodontitis patients

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Scaling and root planning (SRP) is the main therapeutic approach to treating periodontitis. The adjunctive use of local antimicrobials has demonstrated some improvement in outcomes.  The aim of this review was to assess the effect on clinical outcomes of local antimicrobials as adjuncts to SRP, compared to SRP alone or plus placebo, in chronic periodontitis [read the full story…]