This Cochrane review of antifibrinolytic agents for preventing bleeding in people on oral anticoagulants undergoing dental extractions or minor oral surgery included 4 RCTs. Topical tranexamic acid was effective in reducing post-operative bleeding following dental procedures.
[read the full story...]Orthognathic surgery: intra-operative bleeding reduced with tranexamic acid
This review looked at the efficacy of haemostatic adjuncts on intra-operative blood loss in orthognathic surgery. 11 RCTs were included and found that tranexamic acid reduced blood loss by about a third whether used topically or intravenously.
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