Following on from my post yesterday about screening tools for depression in later life, here is a new meta-analysis that explores the efficacy of antidepressants for the treatment of major depressive disorder (MDD) in patients aged ≥ 55 years. The researchers from the University of Modena and Reggio Emilia in Italy just searched PubMed for [read the full story…]
If you are a doctor, nurse or pharmacist involved in the care of patients with depression, you may like to take this self-directed learning module on selective serotonin reuptake inhibitors (SSRI) antidepressants produced by the Medicines and Healthcare products Regulatory Agency (MHRA). The free online training outlines the key risks of this important class of [read the full story…]
All mental health professionals are well aware that depression and alcohol misuse frequently go hand in hand. One condition often complicates and affects the outcome of the other. NICE guidelines recommend treating the alcohol problems first and then after 3-4 weeks of abstinence focus on treating the comorbid mental illness if it’s still present. This [read the full story…]
Bipolar disorder is a complex health condition and the diagnosis of bipolar depression is a fairly contentious topic. This is because depression occurs in bipolar disorder alongside a wide range of symptoms of mood elevation. Some patients have depressive episodes as well as severely elevated mood during the course of their illness, whereas other patients [read the full story…]
This is an unusual randomised controlled trial conducted by a research team from Arkin Institute for Mental Health in Amsterdam and funded by Eli Lilly. The study measures social functioning as an outcome, as well as the more commonly measured depression symptoms. It aims to find out how much psychotherapy is optimal for depressed people [read the full story…]
Obsessive compulsive disorder (OCD) is a condition that is usually associated with obsessive thoughts and compulsive behaviour. It’s one of the most common mental health problems in young people, with an estimated 5% of children and teenagers suffering from the chronic condition. Studies have shown that SSRI antidepressants and cognitive behavioural therapy (CBT) are both [read the full story…]
Seasonal affective disorder (winter depression) is a type of depression that recurs in the autumn and lasts until the spring. It is similar to regular depression except sufferers are usually very tired and have an increase in their appetite. It is more common in countries with few daylight hours in winter. People with seasonal affective [read the full story…]
A large number of systematic reviews and guidelines have been published in recent years to assist clinicians in prescribing the best antidepressants for treating depression. This new meta-analysis conducted by researchers from Austria and the US, sets out to compare the benefits and harms of second generation antidepressant drugs in the treatment of major depressive [read the full story…]
Children with obsessive-compulsive disorder (OCD) are often prescribed antidepressant drugs (serotonin reuptake inhibitors – SRI), but many only partially respond to this treatment. This randomised controlled trial conducted by researchers from the University of Pennsylvania School of Medicine, examined the effects of augmenting the antidepressant medication with cognitive behaviour therapy (CBT). The trial was quite [read the full story…]
In November 2007, the US Food and Drug Administration required that black box warnings be placed on all antidepressant medications warning they may result in increased risk of suicidal tendencies in children and adolescents. It is now considered good practice that patients of all ages who initiate antidepressants should be monitored for clinical worsening or [read the full story…]
